Carbadox

Carbadox
Names
IUPAC names
methyl (2E)-2-[(1,4-dioxidoquinoxalin-2-yl)
methylene]hydrazinecarboxylate
Identifiers
6804-07-5 N
ChEMBL ChEMBL13779 YesY
ChemSpider 10606106 YesY
EC Number 229-879-0
Jmol 3D model Interactive image
PubChem 5353472
RTECS number FE2779000
Properties
C11H10N4O4
Molar mass 262.22 g/mol
Appearance Yellow crystals
Density 1.44 g/cm3
Melting point 239.5 °C
Insoluble
Hazards
F, T
R/S statement R: R45, R11, R22
S: S53, S45
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Carbadox is a veterinary drug that combats bacterial infection in swine, particularly swine dysentery. In early 2004, it was banned by the Canadian government as a livestock feed additive and for human consumption, since it is carcinogenic and induces birth defects, as was shown in animal experiments.[1] The European Union also forbids the use of carbadox at any level.[2] It is approved in the United States for use in swine for up to 42 days before slaughter,[3] but in 2016, the United States Food and Drug Administration moved to ban its use in pork, citing a potential cancer risk to humans.[4] Australia forbids the use of carbadox in food producing animals.[5]

References

  1. Maximum Residue Limits, Health Canada, retrieved 2010-07-27
  2. Ungemach, Fritz R. "WHO Food Additives Series: 51 CARBADOX (addendum)". WHO Food Additives Series. INCHEM. Retrieved 23 Mar 2015.
  3. "21CFR 558.115". Code of Federal Regulations. FDA. 1 Apr 2014. Retrieved 23 Mar 2015.
  4. Fox, Maggie. "FDA Moves to Ban Cancer-Causing Pork Antibiotic". NBC News. Retrieved 9 Apr 2016.
  5. Substances Not Permitted for use on Food-Producing Animals in Australia, Australian Pesticides and Veterinary Medicines Authority, retrieved 2010-08-31


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