Cariporide

Cariporide
Systematic (IUPAC) name

N-(Diaminomethylidene)-3-methanesulfonyl-4-(propan-2-yl)benzamide
Identifiers
CAS Number	159138-80-4
ATC code	none
PubChem	CID 151172
ChemSpider	133240
UNII	7E3392891K^Y
ChEMBL	CHEMBL436559
Synonyms	HOE642
Chemical data
Formula	C₁₂H₁₇N₃O₃S
Molar mass	283.3 g/mol
SMILES O=S(=O)(c1cc(ccc1C(C)C)C(=O)/N=C(\N)N)C
InChI InChI=1S/C12H17N3O3S/c1-7(2)9-5-4-8(11(16)15-12(13)14)6-10(9)19(3,17)18/h4-7H,1-3H3,(H4,13,14,15,16) Key:IWXNYAIICFKCTM-UHFFFAOYSA-N

Cariporide is a selective Na⁺/H⁺ exchange inhibitor. Cariporide has been shown to actively suppress the cell death caused by oxidative stress.^[1]

References

↑ Yeshmina; et al. (2003). "Cariporide (HOE642), a selective Na+-H+ exchange inhibitor, inhibits the mitochondrial death pathway". Circulation 108 (18): 2275–81. doi:10.1161/01.CIR.0000093277.20968.C7. PMID 14568900.

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