Carotenoid-9',10'-cleaving dioxygenase

Carotenoid-9',10'-cleaving dioxygenase
Identifiers
EC number	1.13.11.71
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Carotenoid-9',10'-cleaving dioxygenase (EC 1.13.11.71, BCO₂ (gene), beta-carotene 9',10'-monooxygenase (misleading)) is an enzyme with systematic name all-trans-beta-carotene:O₂ oxidoreductase (9',10'-cleaving).^[1][2] This enzyme catalyses the following chemical reaction

all-trans-beta-carotene + O₂ $\rightleftharpoons$ all-trans-10'-apo-beta-carotenal + beta-ionone

Carotenoid-9',10'-cleaving dioxygenase contains Fe²⁺.

References

1. Kiefer, C., Hessel, S., Lampert, J.M., Vogt, K., Lederer, M.O., Breithaupt, D.E. and von Lintig, J. (2001). "Identification and characterization of a mammalian enzyme catalyzing the asymmetric oxidative cleavage of provitamin A". J. Biol. Chem. 276: 14110–14116. doi:10.1074/jbc.M011510200. PMID 11278918.
2. Lindqvist, A., He, Y.G. and Andersson, S. (2005). "Cell type-specific expression of β-carotene 9′,10′-monooxygenase in human tissues". J. Histochem. Cytochem. 53 (11): 1403–1412. doi:10.1369/jhc.5A6705.2005. PMID 15983114.

External links

• Carotenoid-9',10'-cleaving dioxygenase at the US National Library of Medicine Medical Subject Headings (MeSH)