Chris Sander (scientist)

Chris Sander

Chris Sander speaking at ISMB in 2010
Born Germany
Institutions Dana Farber Cancer Institute
Memorial Sloan–Kettering Cancer Center
Rockefeller University
Cornell University
Weizmann Institute of Science[1]
Alma mater University of Berlin
University of California, Berkeley[2]
Thesis Analytic properties of bound state wave functions (1975)
Doctoral students Burkhard Rost
Known for Bioinformatics
Computational biology
Cancer genomics[3]
Notable awards ISCB Senior Scientist Awards (2010)[4]
Website
www.mskcc.org/research/lab/chris-sander

Chris Sander is a computational biologist and chair of the Computational Biology Programme at the Memorial Sloan–Kettering Cancer Center in New York City.[5][6][7][8][9][10][11]

Education

Sander originally trained as a physicist receiving his undergraduate degree from the University of Berlin in 1967.[2] After a period studying at the University of California, Berkeley and the Niels Bohr Institute in Copenhagen,[2][12] he gained his PhD degree in theoretical physics from the State University of New York in 1975. His thesis was titled Analytic properties of bound state wave functions.[13]

Research

Sander credits his move from theoretical physics to computational biology to Fred Sanger's 1977 landmark paper in Nature,[14] in which the nucleotide sequence of bacteriophage φX174 was published.[2] Sander has made many contributions to the field of structural bioinformatics including developing tools such as the Families of Structurally Similar Proteins (FSSP) database[15] and the DSSP algorithm for assigning secondary structure to the amino acids of a protein, given the atomic-resolution coordinates of that protein.[16]

Sander has also worked at the European Bioinformatics Institute, has served as chief information officer for the biopharmaceutical company Millennium Pharmaceuticals and has been an advisor to IBM's Deep Computing Initiative, which produced the Deep Blue chess computer.[17]

Roles and Honours

Sander is a former Executive Editor for the journal Bioinformatics. In 2014 he was appointed one of the first Honorary Editors of Bioinformatics.[18]

Sander was awarded the ISCB Accomplishment by a Senior Scientist Award in 2010.[12]

Personal life

Sander is brother of German actor Otto Sander.[19]

References

  1. ↑ Lifson, Shneior; Sander, Christian (1979). "Antiparallel and parallel β-strands differ in amino acid residue preferences". Nature 282 (5734): 109–111. doi:10.1038/282109a0. PMID 503185.
  2. 1 2 3 4 "At Work: Computational Biology Program Chair Chris Sander | Memorial Sloan-Kettering Cancer Center". Archived from the original on 2013-08-20.
  3. ↑ Holm, L.; Sander, C. (1993). "Protein Structure Comparison by Alignment of Distance Matrices". Journal of Molecular Biology 233 (1): 123–138. doi:10.1006/jmbi.1993.1489. PMID 8377180.
  4. ↑ McKay, B. M.; Sansom, C. (2010). "2010 ISCB Overton Prize Awarded to Steven E. Brenner". PLoS Computational Biology 6 (6): e1000831. doi:10.1371/journal.pcbi.1000831. PMC 2891695. PMID 20585610.
  5. ↑ Chris Sander's publications indexed by the DBLP Bibliography Server at the University of Trier
  6. ↑ Chris Sander's publications indexed by Google Scholar, a service provided by Google
  7. ↑ List of publications from Microsoft Academic Search
  8. ↑ Chris Sander's publications indexed by the Scopus bibliographic database, a service provided by Elsevier.
  9. ↑ John, B.; Enright, A. J.; Aravin, A.; Tuschl, T.; Sander, C.; Marks, D. S. (2004). "Human MicroRNA Targets". PLoS Biology 2 (11): e363. doi:10.1371/journal.pbio.0020363. PMC 521178. PMID 15502875.
  10. ↑ Rost, B.; Sander, C. (1993). "Prediction of Protein Secondary Structure at Better than 70% Accuracy". Journal of Molecular Biology 232 (2): 584–599. doi:10.1006/jmbi.1993.1413. PMID 8345525.
  11. ↑ Sander, C.; Schulz, G. E. (1979). "Degeneracy of the information contained in amino acid sequences: Evidence from overlaid genes". Journal of Molecular Evolution 13 (3): 245–252. doi:10.1007/BF01739483. PMID 228047.
  12. 1 2 http://www.iscb.org/iscb-awards/1133
  13. ↑ "INIS Collection Search - Single Result". Retrieved 13 August 2015.
  14. ↑ Sanger, F.; Air, G. M.; Barrell, B. G.; Brown, N. L.; Coulson, A. R.; Fiddes, J. C.; Hutchison, C. A.; Slocombe, P. M.; Smith, M. (24 February 1977). "Nucleotide sequence of bacteriophage φX174 DNA". Nature 265 (5596): 687–695. doi:10.1038/265687a0. PMID 870828.
  15. ↑ Holm L, Ouzounis C, Sander C, Tuparev G, Vriend G (1992). "A database of protein structure families with common folding motifs". Protein Science 1 (12): 1691–1698. doi:10.1002/pro.5560011217. PMC 2142138. PMID 1304898.
  16. ↑ Kabsch, W.; Sander, C. (1983). "Dictionary of protein secondary structure: Pattern recognition of hydrogen-bonded and geometrical features". Biopolymers 22 (12): 2577–2637. doi:10.1002/bip.360221211. PMID 6667333.
  17. ↑ "Bio-IT World: Horizons - Chris Sander". Retrieved 13 August 2015.
  18. ↑ "15 years of "Bioinformatics"". Bioinformatics (Oxford, England) 30 (6): 747. 2014. doi:10.1093/bioinformatics/btu076. PMID 24642573.
  19. ↑ Biography for Otto Sander at the Internet Movie Database
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