Chromium(III) nicotinate

Systematic (IUPAC) name
Chromium(3+) tri(pyridine-3-carboxylate)
Identifiers
CAS Number	64452-96-6
ATC code	None
PubChem	CID 56843898
ChemSpider	8085563
Synonyms	Chromium trinicotinate
Chemical data
Formula	C18H12CrN3O6
Molar mass	418.30 g/mol
SMILES [Cr+3].[O-]C(=O)c1cccnc1.[O-]C(=O)c1cccnc1.[O-]C(=O)c1cccnc1
InChI InChI=1S/3C6H5NO2.Cr/c3*8-6(9)5-2-1-3-7-4-5;/h3*1-4H,(H,8,9);/q;;;+3/p-3 Key:MSPQQAUTCRWLGR-UHFFFAOYSA-K

Chromium(III) nicotinate is an ionic substance used for chromium supplementation in some nutritional products, where it is also referred to as chromium polynicotinate. It appears in products that are referred to as a medical food used for nutritional support for conditions associated with diabetes mellitus type 2. The product is also known as "niacin-bound chromium".^[1]

Chemistry

Chromium(III) nicotinate contains three nicotinic acid units per chromium ion; that is, it is the trinicotinate of chromium(III). The substance that is used in supplements and called "chromium polynicotinate" is said to be a mixture of the trinicotinate and the dinicotinate, with the former dominating.^[2]

See also

• Chromium(III) picolinate

References

1. Preuss, H. G.; Bagchi, D.; Bagchi, M.; Rao, C. V. S.; Dey, D. K.; Satyanarayana, S. (May 2004). "Effects of a natural extract of (–)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss". Diabetes, Obesity & Metabolism 6 (3): 171–180. doi:10.1111/j.1462-8902.2004.00328.x. PMID 15056124.
2. "Mixture of chromium di- and tri-nicotinate as a source of chromium added for nutritional purposes in food supplements and in foods for particular nutritional uses" (PDF). The EFSA Journal 887: 1–24. 2008. line feed character in |title= at position 59 (help)