Chromosome 13 (human)

Chromosome 13 (human)

Pair of human chromosome 13 (after G-banding).
One is from mother, one is from father.

Chromosome 13 pair in human male karyogram.
Features
Length (bp) 114,364,328 bp
Number of genes 993
Type Autosome
Centromere position Acrocentric [1]
Identifiers
RefSeq NC_000013
GenBank CM000675
Map of Chromosome 13
Ideogram of human chromosome 13. Mbp means mega base pair. See locus for other notation.

Chromosome 13 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 13 spans about 114 million base pairs (the building material of DNA) and represents between 3.5 and 4% of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the number of genes varies. Chromosome 13 likely contains between 300 and 700 genes.

Genes

The following are some of the genes located on chromosome 13:

Diseases and disorders

The following diseases and disorders are some of those related to genes on chromosome 13:

Chromosomal conditions

The following conditions are caused by changes in the structure or number of copies of chromosome 13:

References

  • Baud O, Cormier-Daire V, Lyonnet S, Desjardins L, Turleau C, Doz F (1999). "Dysmorphic phenotype and neurological impairment in 22 retinoblastoma patients with constitutional cytogenetic 13q deletion". Clin Genet 55 (6): 478–82. doi:10.1034/j.1399-0004.1999.550614.x. PMID 10450867. 
  • Dunham A, Matthews LH, Burton J, Ashurst JL, Howe KL, Ashcroft KJ, Beare DM, Burford DC, Hunt SE, Griffiths-Jones S, Jones MC, Keenan SJ, Oliver K, Scott CE, Ainscough R, Almeida JP, Ambrose KD, Andrews DT, Ashwell RI, Babbage AK, Bagguley CL, Bailey J, Bannerjee R, Barlow KF, Bates K, Beasley H, Bird CP, Bray-Allen S, Brown AJ, Brown JY, Burrill W, Carder C, Carter NP, Chapman JC, Clamp ME, Clark SY, Clarke G, Clee CM, Clegg SC, Cobley V, Collins JE, Corby N, Coville GJ, Deloukas P, Dhami P, Dunham I, Dunn M, Earthrowl ME, Ellington AG, Faulkner L, Frankish AG, Frankland J, French L, Garner P, Garnett J, Gilbert JG, Gilson CJ, Ghori J, Grafham DV, Gribble SM, Griffiths C, Hall RE, Hammond S, Harley JL, Hart EA, Heath PD, Howden PJ, Huckle EJ, Hunt PJ, Hunt AR, Johnson C, Johnson D, Kay M, Kimberley AM, King A, Laird GK, Langford CJ, Lawlor S, Leongamornlert DA, Lloyd DM, Lloyd C, Loveland JE, Lovell J, Martin S, Mashreghi-Mohammadi M, McLaren SJ, McMurray A, Milne S, Moore MJ, Nickerson T, Palmer SA, Pearce AV, Peck AI, Pelan S, Phillimore B, Porter KM, Rice CM, Searle S, Sehra HK, Shownkeen R, Skuce CD, Smith M, Steward CA, Sycamore N, Tester J, Thomas DW, Tracey A, Tromans A, Tubby B, Wall M, Wallis JM, West AP, Whitehead SL, Willey DL, Wilming L, Wray PW, Wright MW, Young L, Coulson A, Durbin R, Hubbard T, Sulston JE, Beck S, Bentley DR, Rogers J, Ross MT (2004). "The DNA sequence and analysis of human chromosome 13". Nature 428 (6982): 522–8. doi:10.1038/nature02379. PMC 2665288. PMID 15057823. 
  • Gilbert F (2000). "Chromosome 13". Genet Test 4 (1): 85–94. doi:10.1089/109065700316543. PMID 10794368. 
  • Kivela T, Tuppurainen K, Riikonen P, Vapalahti M (2003). "Retinoblastoma associated with chromosomal 13q14 deletion mosaicism". Ophthalmology 110 (10): 1983–8. doi:10.1016/S0161-6420(03)00484-6. PMID 14522775. 
Wikimedia Commons has media related to Human chromosome 13.
  1. "Table 2.3: Human chromosome groups". Human Molecular Genetics (2nd ed.). Garland Science. 1999.
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