Co-danthrusate

Co-danthrusate
Combination of
ChemSpider none

Co-danthrusate is a combination of dantron and docusate. Dantron is a mild peristaltic stimulant which acts on the lower bowel to encourage normal bowel movement without causing irritation. It belongs to the group of medicines under the term stimulant laxative.[1] It stimulates the nerves in the stomach wall which causes the stomach muscles to contract. This medicine is used for analgesic-induced constipation. It takes six to twelve hours to work.[2] This can cause discoloration of urine and bowel and liver tumors.[3]

Co-danthramer is dantron plus poloxamer. It is (in the U.K.) only to be prescribed to terminally ill patients due to carcinogen reactions in rats. It is often prescribed to people taking long term opioid, because it relaxes the effect of opioid induced constipation. It will not alleviate the symptoms of opioid induced delayed gastric emptying and abdominal cramps.[4]

See also

References

  1. ↑ http://patient.info/doctor/constipation-in-adults-pro
  2. ↑ http://web.archive.org/web/20070820141126/http://www.tiscali.co.uk/lifestyle/healthfitness/health_advice/netdoctor/archive/100000561.html
  3. ↑ http://www.epgonline.org/viewdrug.cfm/letter/C/language/LG0001/drugId/DR000022/drugName/Co-danthrusate
  4. ↑ http://clinicalevidence.bmj.com/ceweb/conditions/spc/2407/2407_I5.jsp
This article is issued from Wikipedia - version of the Thursday, November 19, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.