Colworth Medal

Colworth Medal
Awarded for	outstanding research by a young biochemist of any nationality who has carried out the majority of their work in the UK or Republic of Ireland
Sponsor	Biochemical Society
Reward	£3000
Official website	www.biochemistry.org/awards/thecolworthmedal.aspx

The Colworth Medal^[1][2] is awarded annually by the Biochemical Society to an outstanding research biochemist under the age of 35 and working mainly in the United Kingdom. The award is one of the most prestigious recognitions for young scientists in the UK, and was established by Tony James^[3] FRS at Unilever Research and Henry Arnstein of the Biochemical Society and takes its name from a Unilever research laboratory near Bedford in the UK, Colworth House.

The medal was first presented in 1963^[4] and many of those receiving the award are recognised as outstanding scientists achieving international reputations.^[5] The lecture is published in Biochemical Society Transactions, previously Colworth Medal lectures were published in The Biochemical Journal.

Laureates

Laureates of the medal^[5] have included:

• 2017: Markus Ralser^[6]
• 2016: David Grainger^[7]
• 2015: Helen Walden^[8]
• 2014: Madan Babu^[5]
• 2013: Robin C. May^[9]
• 2012: Akhilesh Reddy^[10]
• 2011: Sarah Teichmann^[11]
• 2010: Mark S. Dillingham^[12]
• 2009: Giles E. Hardingham^[13]
• 2008: John Rouse^[14]
• 2007: Frank Sargent^[15]
• 2006: Simon J. Boulton^[16]
• 2005: Ian Collinson^[17]
• 2004: James H. Naismith^[18]
• 2003: David J. Owen^[19]
• 2002: Thomas Owen-Hughes^[19]
• 2001: Andrew D. Sharrocks^[19]
• 2000: Dario Alessi^[20]
• 1999: Nigel Scrutton^[21]
• 1998: David Barford^[22]
• 1997: Stephen P. Jackson^[23]
• 1996: Sheena Radford^[19]
• 1995: Jonathon Pines^[24]
• 1994: R.L. Stephens^[25]
• 1993: Nicholas C. Tonks^[19]
• 1992: Angus I. Lamond^[26]
• 1991: Michael A.J. Ferguson^[27]
• 1990: David W. Melton^[28]
• 1988: Hugh Pelham^[29]
• 1987: C. Peter Downes^[30]
• 1986: Greg Winter^[19]
• 1985: Alec Jeffreys^[31]
• 1984: Miles D. Houslay^[32]
• 1983: Eric Oldfield^[33]
• 1982: David M.J. Lilley^[34]
• 1981: Terence H. Rabbitts^[35]
• 1980: R.A. Flavell^[36]
• 1979: Ronald Laskey^[37]
• 1978: Timothy E. Hardingham^[38]
• 1977: Philip Cohen^[39]
• 1976: George Brownlee^[40]
• 1975: William J. Brammar^[41]
• 1974: David R. Trentham^[42]
• 1973: James C. Metcalfe^[19]
• 1972: John M. Ashworth^[19]
• 1971: A.R. Williamson^[43]
• 1970: Dai Rees^[44]
• 1969: George Radda^[45]
• 1968: Peter B. Garland^[46]
• 1967: L.J. Morris^[47]
• 1966: M.H. Richmond^[48]
• 1965: J.B. Chappell
• 1964: Jamshed R. Tata^[49]
• 1963: Hans Kornberg^[4]

References

1. "colworth medal", New Scientist, June 1971: 642–3
2. Goodwin, Trevor Walworth (1987), History of the Biochemical Society, 1911-1986, Biochemical Society, pp. 50, 66–67
3. Gurr, M. (2012). "Anthony Trafford James. 6 March 1922 -- 7 December 2006". Biographical Memoirs of Fellows of the Royal Society 58: 129–150. doi:10.1098/rsbm.2011.0018.
4. Kornberg, H. L. (1966). "The role and control of the glyoxylate cycle in Escherichia coli". The Biochemical Journal 99 (1): 1–11. doi:10.1042/bj0990001. PMC 1264949. PMID 5337756.
5. "The Colworth Medal". Biochemical Society. Archived from the original on 2014-05-06.
6. "Colworth Medal | The Francis Crick Institute". The Francis Crick Institute. Retrieved 2016-03-31.
7. "2016 Award Winners | Biochemical Society". www.biochemistry.org. Retrieved 2016-03-31.
8. "2015 Winners". www.biochemistry.org. Retrieved 2016-03-31.
9. Smith, L. M.; May, R. C. (2013). "Mechanisms of microbial escape from phagocyte killing". Biochemical Society Transactions 41 (2): 475–90. doi:10.1042/BST20130014. PMID 23514140.
10. Wu, L; Reddy, A. B. (2014). "Rethinking the clockwork: Redox cycles and non-transcriptional control of circadian rhythms". Biochemical Society Transactions 42 (1): 1–10. doi:10.1042/BST20130169. PMID 24450621.
11. Perica, T; Marsh, J. A.; Sousa, F. L.; Natan, E; Colwell, L. J.; Ahnert, S. E.; Teichmann, S. A. (2012). "The emergence of protein complexes: Quaternary structure, dynamics and allostery. Colworth Medal Lecture". Biochemical Society Transactions 40 (3): 475–91. doi:10.1042/BST20120056. PMID 22616857.
12. Dillingham, M. S. (2011). "Superfamily I helicases as modular components of DNA-processing machines". Biochemical Society Transactions 39 (2): 413–23. doi:10.1042/BST0390413. PMID 21428912.
13. Hardingham, G. E. (2009). "Coupling of the NMDA receptor to neuroprotective and neurodestructive events". Biochemical Society Transactions 37 (Pt 6): 1147–60. doi:10.1042/BST0371147. PMC 2837198. PMID 19909238.
14. Rouse, J (2009). "Control of genome stability by SLX protein complexes". Biochemical Society Transactions 37 (Pt 3): 495–510. doi:10.1042/BST0370495. PMID 19442243.
15. Sargent, F (2007). "The twin-arginine transport system: Moving folded proteins across membranes". Biochemical Society Transactions 35 (Pt 5): 835–47. doi:10.1042/BST0350835. PMID 17956229.
16. Boulton, S. J. (2006). "Cellular functions of the BRCA tumour-suppressor proteins". Biochemical Society Transactions 34 (Pt 5): 633–45. doi:10.1042/BST0340633. PMID 17052168.
17. Collinson, I (2005). "The structure of the bacterial protein translocation complex SecYEG". Biochemical Society Transactions 33 (Pt 6): 1225–30. doi:10.1042/BST20051225. PMID 16246086.
18. Naismith, J. H. (2004). "Chemical insights from structural studies of enzymes". Biochemical Society Transactions 32 (Pt 5): 647–54. doi:10.1042/BST0320647. PMID 15493979.
19. "Past recipeints of the Colworth Medal". Biochemical Society. 2013. Archived from the original on December 14, 2013.
20. Alessi, D. R. (2001). "Discovery of PDK1, one of the missing links in insulin signal transduction. Colworth Medal Lecture". Biochemical Society Transactions 29 (Pt 2): 1–14. doi:10.1042/0300-5127:0290001. PMID 11356119.
21. Scrutton, N. S. (1999). "Colworth Medal Lecture. Enzymes in the quantum world". Biochemical Society Transactions 27 (6): 767–79. PMID 10830100.
22. Barford, D (1999). "Colworth Medal Lecture. Structural studies of reversible protein phosphorylation and protein phosphatases". Biochemical Society Transactions 27 (6): 751–66. doi:10.1042/bst0270751. PMID 10830099.
23. Jackson, S. P. (1999). "Colworth Medal lecture. Detection, repair and signalling of DNA double-strand breaks". Biochemical Society Transactions 27 (2): 1–13. doi:10.1042/bst0270001. PMID 10093700.
24. Pines, J (1996). "Cyclin from sea urchins to He Las: Making the human cell cycle". Biochemical Society Transactions 24 (1): 15–33. doi:10.1042/bst0240015. PMID 8674643.
25. Stephens, L (1995). "Colworth Medal Lecture. Molecules mediating signals". Biochemical Society Transactions 23 (2): 207–21. doi:10.1042/bst0230207. PMID 7672227.
26. Lamond, A. I. (1993). "2'-O-alkyloligoribonucleotides: Probes for studying the biochemistry and cell biology of RNA processing". Biochemical Society Transactions 21 (1): 1–8. doi:10.1042/bst0210001. PMID 8449268.
27. Ferguson, M. A. (1992). "Colworth Medal Lecture. Glycosyl-phosphatidylinositol membrane anchors: The tale of a tail". Biochemical Society Transactions 20 (2): 243–56. doi:10.1042/bst0200243. PMID 1397606.
28. Melton, D. W. (1990). "The use of gene targeting to develop animal models for human genetic diseases". Biochemical Society Transactions 18 (6): 1035–9. doi:10.1042/bst0181035. PMID 2088798.
29. Pelham, H. R. (1989). "The selectivity of secretion: Protein sorting in the endoplasmic reticulum". Biochemical Society Transactions 17 (5): 795–802. doi:10.1042/bst0170795. PMID 2515980.
30. Downes, C. P. (1989). "Twenty-fifth Colworth medal lecture. The cellular functions of myo-inositol". Biochemical Society Transactions 17 (2): 259–68. PMID 2546836.
31. Jeffreys, A. J. (1987). "Highly variable minisatellites and DNA fingerprints". Biochemical Society Transactions 15 (3): 309–17. doi:10.1042/bst0150309. PMID 2887471.
32. Houslay, M. D. (1986). "Insulin, glucagon and the receptor-mediated control of cyclic AMP concentrations in liver. Twenty-second Colworth medal lecture". Biochemical Society Transactions 14 (2): 183–93. doi:10.1042/bst0140183. PMID 3011541.
33. Oldfield, E (1988). "Spectroscopic studies of lipids and biological membranes. Twenty-first Colworth medal lecture". Biochemical Society Transactions 16 (1): 1–10. PMID 3277879.
34. Lilley, D. M. (1983). "Structural perturbation in supercoiled DNA: Hypersensitivity to modification by a single-strand-selective chemical reagent conferred by inverted repeat sequences". Nucleic Acids Research 11 (10): 3097–112. doi:10.1093/nar/11.10.3097. PMC 325951. PMID 6304622.
35. Rabbitts, T. H. (1983). "The human immunoglobulin genes. The nineteenth Colworth medal lecture". Biochemical Society Transactions 11 (2): 119–26. PMID 6420211.
36. Flavell, R. A. (1983). "The globin genes of rabbit and man. The eighteenth Colworth medal lecture". Biochemical Society Transactions 11 (2): 111–8. doi:10.1042/bst0110111. PMID 6198222.
37. Laskey, R. A. (1981). "Molecular mechanisms of chromatin assembly". Biochemical Society Transactions 9 (4): 263–70. doi:10.1042/bst0090263. PMID 6266896.
38. Hardingham, T (1981). "Proteoglycans: Their structure, interactions and molecular organization in cartilage". Biochemical Society Transactions 9 (6): 489–97. doi:10.1042/bst0090489. PMID 7308557.
39. Cohen, P (1979). "The hormonal control of glycogen metabolism in mammalian muscle by multivalent phosphorylation". Biochemical Society Transactions 7 (3): 459–80. doi:10.1042/bst0070459. PMID 221283.
40. Brownlee, G. G. (1979). "The Fourteenth Colworth Medal Lecture Sequencing eukaryotic genes or the anatomy of DNA". Biochemical Society Transactions 7 (2): 279–96. doi:10.1042/bst0070279. PMID 570938.
41. Brammar, W. J. (1977). "The thirteenth Colworth Medal Lecture: The construction in vitro and exploitation of transducing derivatives of bacteriophage lambda". Biochemical Society Transactions 5 (6): 1633–52. doi:10.1042/bst0051633. PMID 340298.
42. Trentham, D. R. (1977). "The twelfth Colworth Medal lecture. The adenosine triphosphatase reactions of myosin and actomyosin and their relation to energy transduction in muscle". Biochemical Society Transactions 5 (1): 5–22. doi:10.1042/bst0050005. PMID 142675.
43. Williamson, A. R. (1972). "Extent and control of antibody diversity". The Biochemical Journal 130 (2): 325–33. doi:10.1042/bj1300325. PMC 1174411. PMID 4124148.
44. Rees, D. A. (1972). "Shapely polysaccharides. The eighth Colworth medal lecture". The Biochemical Journal 126 (2): 257–73. doi:10.1042/bj1260257. PMC 1178377. PMID 4561024.
45. Radda, G. K. (1971). "Enzyme and membrane conformation in biochemical control". The Biochemical Journal 122 (4): 385–96. doi:10.1042/bj1220385. PMC 1176792. PMID 4942951.
46. Garland, P. B. (1970). "Biochemical applications of continuous culture: Energy-conservation mechanisms in Torulopsis utilis". The Biochemical Journal 118 (3): 329–39. doi:10.1042/bj1180329. PMC 1179196. PMID 4920880.
47. Morris, L. J. (1970). "Mechanisms and stereochemistry in fatty acid metabolism". The Biochemical Journal 118 (5): 681–93. doi:10.1042/bj1180681g. PMC 1179276. PMID 4920387.
48. Richmond, M. H. (1969). "Extrachromosomal elements and the spread of antibiotic resistance in bacteria". The Biochemical Journal 113 (2): 225–34. doi:10.1042/bj1130225. PMC 1184627. PMID 5808311.
49. Tata, J. R. (1967). "The formation and distribution of ribosomes during hormone-induced growth and development". The Biochemical Journal 104 (1): 1–16. doi:10.1042/bj1040001. PMC 1270539. PMID 5340734.