Comedocarcinoma
Comedocarcinoma |
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Classification and external resources |
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ICD-O |
M8501/3 |
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Comedocarcinoma is one kind of breast cancer which is most commonly very early-stage [1][2] which demonstrates central necrosis.[3] It is a usually a type of ductal carcinoma in situ. Comedo carcinomas are usually non-infiltrating and intraductal tumors. However, there have been accounts of comedocarcinoma which has then diversified into other cell types and developed into infiltrating (invasive) ductal carcinoma.[4] Recurrence and survival rates differ for invasive breast cancer which has originated as comedocarcinoma compared with other types of cancer cells.[5]
The duct will have characteristic necrotic tissue with calcification that feels cord-like. Squeezing the duct will yield inspissated material that is cheese-like and similar in consistency to toothpaste.
Comedocarcinoma has also been described as a histopathological type of Sebaceous carcinoma
References
This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".
External links