Cucumisin

Cucumisin
Identifiers
EC number	3.4.21.25
CAS number	82062-89-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Cucumisin (EC 3.4.21.25, euphorbain, solanain, hurain, tabernamontanain) is an enzyme.^{[1][2][3][4][5][6][7]} This enzyme catalyses the following chemical reaction

Hydrolysis of proteins with broad specificity

This enzyme is isolated from the sarcocarp of the musk melon (Cucumis melo).

References

1. Greenberg, D.M. and Winnick, T. (1940). "Plant proteases. I. Activation-inhibition reactions". J. Biol. Chem. 135: 761–773.
2. Jaffé, W.G. (1943). "Hurain, a new plant protease from Hura crepitans". J. Biol. Chem. 149: 1–7.
3. Jaffé, W.G. (1943). "A new vegetable proteolytic enzyme of the papain class". Rev. Brasil Biol. 3: 149–157.
4. Kaneda, M. and Toninaga, N. (1975). "Isolation and characterization of a proteinase from the sarcocarp of melon fruit". J. Biochem. (Tokyo) 78: 1287–1296. PMID 5423.
5. Kaneda, M., Ohmine, H., Yonezawa, H. and Tominaga, N. (1984). "Amino acid sequence around the reactive site of cucumisin from melon fruit". J. Biochem. (Tokyo) 95: 825–829. PMID 6427203.
6. Lynn, K.R. and Clevette-Radford, N.A. (1985). "Two proteases from the latex of Elaeophorbia drupifera". Phytochemistry 24: 2843–2845. doi:10.1016/0031-9422(85)80011-x.
7. Kaneda, N., Minematsu, Y., Powers, J.C. and Tominaga, N. (1986). "Specificity of cucumisin in hydrolysis of peptide thiobenzyl esters". Agric. Biol. Chem. 50: 1075–1076. doi:10.1271/bbb1961.50.1075.

External links

• Cucumisin at the US National Library of Medicine Medical Subject Headings (MeSH)