D-glutamyltransferase
In enzymology, a D-glutamyltransferase (EC 2.3.2.1) is an enzyme that catalyzes the chemical reaction
- L(or D)-glutamine + D-glutamyl-peptide NH3 + 5-glutamyl-D-glutamyl-peptide
The 3 substrates of this enzyme are L-glutamine, D-glutamine, and D-glutamyl-peptide, whereas its two products are NH3 and 5-glutamyl-D-glutamyl-peptide.
This enzyme belongs to the family of transferases, specifically the aminoacyltransferases. The systematic name of this enzyme class is glutamine:D-glutamyl-peptide 5-glutamyltransferase. Other names in common use include D-glutamyl transpeptidase, and D-gamma-glutamyl transpeptidase. This enzyme participates in d-glutamine and d-glutamate metabolism.
References
- Williams WJ, Litwin J and Thorne CB (1955). "Further studies on the biosynthesis of gamma-glutamyl peptides by transfer reactions". J. Biol. Chem. 212: 427–438.
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