D-proline dehydrogenase

D-proline dehydrogenase (EC 1.5.99.13, D-Pro DH, D-Pro dehydrogenase, dye-linked D-proline dehydrogenase) is an enzyme with systematic name D-proline:acceptor oxidoreductase.^[1]^[2] This enzyme catalyses the following chemical reaction

D-proline + acceptor

\rightleftharpoons

1-pyrroline-2-carboxylate + reduced acceptor

This enzyme is a flavoprotein (FAD).

References

↑ Tani, Y., Tanaka, K., Yabutani, T., Mishima, Y., Sakuraba, H., Ohshima, T. and Motonaka, J. (2008). "Development of a D-amino acids electrochemical sensor based on immobilization of thermostable D-proline dehydrogenase within agar gel membrane". Anal. Chim. Acta 619 (2): 215–220. doi:10.1016/j.aca.2008.04.063. PMID 18558115.
↑ Satomura, T., Kawakami, R., Sakuraba, H. and Ohshima, T. (2002). "Dye-linked D-proline dehydrogenase from hyperthermophilic archaeon Pyrobaculum islandicum is a novel FAD-dependent amino acid dehydrogenase". J. Biol. Chem. 277 (15): 12861–12867. doi:10.1074/jbc.M112272200. PMID 11823469.

External links

D-proline dehydrogenase at the US National Library of Medicine Medical Subject Headings (MeSH)

Oxidoreductases: CH-NH (EC 1.5)

1.5.1: NAD or NADP acceptor	Dihydrofolate reductase Saccharopine dehydrogenase Methylenetetrahydrofolate reductase

1.5.3: oxygen acceptor	Dihydrobenzophenanthridine oxidase Sarcosine oxidase Proline oxidase

1.5.5: quinone acceptor	Electron-transferring-flavoprotein dehydrogenase

1.5.99	Sarcosine dehydrogenase Cytokinin dehydrogenase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

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