DEFA1B

Defensin, alpha 1B
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 2KHT, 2PM1, 3GNY, 3H6C, 3HJ2, 3HJD, 3LO1, 3LO2, 3LO4, 3LO6, 3LO9, 3LOE, 3LVX, 4DU0, 4LB1, 4LB7, 4LBB, 4LBF
Identifiers
Symbols	DEFA1B ; HNP-1; HP-1; HP1
External IDs	HomoloGene: 128756 GeneCards: DEFA1B Gene
Gene ontology Cellular component • extracellular region • extracellular space • Golgi lumen • extracellular matrix • azurophil granule lumen • extracellular exosome Biological process • innate immune response in mucosa • chemotaxis • immune response • antibacterial humoral response • intracellular estrogen receptor signaling pathway • killing of cells of other organism • innate immune response • defense response to Gram-positive bacterium • defense response to fungus • defense response to virus Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	728358	n/a
Ensembl	ENSG00000206047	n/a
UniProt	P59665	n/a
RefSeq (mRNA)	NM_001042500	n/a
RefSeq (protein)	NP_001035965	n/a
Location (UCSC)	Chr 8: 6.98 – 6.98 Mb	n/a
PubMed search		n/a

Defensin, alpha 1B a human protein that is encoded by the DEFA1B gene.^[1]

See also

• defensin

References

1. "Entrez Gene: defensin".

Further reading

• Kocsis AK, Ocsovszky I, Tiszlavicz L; et al. (2009). "Helicobacter pylori induces the release of alpha-defensin by human granulocytes.". Inflamm. Res. 58 (5): 241–7. doi:10.1007/s00011-008-8100-z. PMID 19169650.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Aldred PM, Hollox EJ, Armour JA (2005). "Copy number polymorphism and expression level variation of the human alpha-defensin genes DEFA1 and DEFA3.". Hum. Mol. Genet. 14 (14): 2045–52. doi:10.1093/hmg/ddi209. PMID 15944200.