DNASE1L1

Deoxyribonuclease I-like 1
Identifiers
Symbols DNASE1L1 ; DNAS1L1; DNASEX; DNL1L; G4.8; XIB
External IDs OMIM: 300081 MGI: 109628 HomoloGene: 4896 GeneCards: DNASE1L1 Gene
EC number 3.1.21.-
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 1774 69537
Ensembl ENSG00000013563 ENSMUSG00000019088
UniProt P49184 Q9D7J6
RefSeq (mRNA) NM_001009932 NM_001172154
RefSeq (protein) NP_001009932 NP_001165625
Location (UCSC) Chr X:
154.4 – 154.41 Mb
Chr X:
74.27 – 74.28 Mb
PubMed search

Deoxyribonuclease-1-like 1 is an enzyme that in humans is encoded by the DNASE1L1 gene.[1][2][3]

This gene encodes a member of the deoxyribonuclease family and the protein shows high sequence similarity to lysosomal DNase I. Alternate transcriptional splice variants, encoding the same protein, have been characterized.[3]

References

  1. Parrish JE, Ciccodicola A, Wehhert M, Cox GF, Chen E, Nelson DL (Feb 1996). "A muscle-specific DNase I-like gene in human Xq28". Hum Mol Genet 4 (9): 1557–64. doi:10.1093/hmg/4.9.1557. PMID 8541839.
  2. Pergolizzi R, Appierto V, Bosetti A, DeBellis GL, Rovida E, Biunno I (Jul 1996). "Cloning of a gene encoding a DNase I-like endonuclease in the human Xq28 region". Gene 168 (2): 267–70. doi:10.1016/0378-1119(95)00741-5. PMID 8654957.
  3. 1 2 "Entrez Gene: DNASE1L1 deoxyribonuclease I-like 1".

Further reading

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