DNA topoisomerase
| DNA topoisomerase | |||||||||
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| Identifiers | |||||||||
| EC number | 5.99.1.2 | ||||||||
| CAS number | 80449-01-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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DNA topoisomerase (EC 5.99.1.2, type I DNA topoisomerase, untwisting enzyme, relaxing enzyme, nicking-closing enzyme, swivelase, omega-protein, deoxyribonucleate topoisomerase) is an enzyme with systematic name DNA topoisomerase.[1] This enzyme catalyses the following chemical reaction
- ATP-independent breakage of single-stranded DNA, followed by passage and rejoining
These enzymes bring about the conversion of one topological isomer of DNA into another.
References
- ↑ Gellert, M. (1981). "DNA topoisomerases". Annu. Rev. Biochem. 50: 879–910. doi:10.1146/annurev.bi.50.070181.004311. PMID 6267993.
See also
External links
- DNA topoisomerase at the US National Library of Medicine Medical Subject Headings (MeSH)
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