DOK3
| Docking protein 3 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | DOK3 ; DOKL | ||||||||||||
| External IDs | OMIM: 611435 MGI: 1351490 HomoloGene: 8448 GeneCards: DOK3 Gene | ||||||||||||
| |||||||||||||
| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 79930 | 27261 | |||||||||||
| Ensembl | ENSG00000146094 | ENSMUSG00000035711 | |||||||||||
| UniProt | Q7L591 | Q9QZK7 | |||||||||||
| RefSeq (mRNA) | NM_001144875 | NM_013739 | |||||||||||
| RefSeq (protein) | NP_001138347 | NP_038767 | |||||||||||
| Location (UCSC) |
Chr 5: 177.5 – 177.51 Mb |
Chr 13: 55.52 – 55.53 Mb | |||||||||||
| PubMed search | |||||||||||||
Docking protein 3 is a protein that in humans is encoded by the DOK3 gene.[1][2][3]
References
- ↑ Lemay S, Davidson D, Latour S, Veillette A (Apr 2000). "Dok-3, a Novel Adapter Molecule Involved in the Negative Regulation of Immunoreceptor Signaling". Mol Cell Biol 20 (8): 2743–54. doi:10.1128/MCB.20.8.2743-2754.2000. PMC 85490. PMID 10733577.
- ↑ Favre C, Gerard A, Clauzier E, Pontarotti P, Olive D, Nunes JA (Feb 2003). "DOK4 and DOK5: new Dok-related genes expressed in human T cells". Genes Immun 4 (1): 40–5. doi:10.1038/sj.gene.6363891. PMID 12595900.
- ↑ "Entrez Gene: DOK3 docking protein 3".
Further reading
- Cong F, Yuan B, Goff SP (2000). "Characterization of a Novel Member of the DOK Family That Binds and Modulates Abl Signaling". Mol. Cell. Biol. 19 (12): 8314–25. PMC 84915. PMID 10567556.
- Grimm J, Sachs M, Britsch S, et al. (2001). "Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation". J. Cell Biol. 154 (2): 345–54. doi:10.1083/jcb.200102032. PMC 2150770. PMID 11470823.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Robson JD, Davidson D, Veillette A (2004). "Inhibition of the Jun N-Terminal Protein Kinase Pathway by SHIP-1, a Lipid Phosphatase That Interacts with the Adaptor Molecule Dok-3". Mol. Cell. Biol. 24 (6): 2332–43. doi:10.1128/MCB.24.6.2332-2343.2004. PMC 355862. PMID 14993273.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Honma M, Higuchi O, Shirakata M, et al. (2007). "Dok-3 sequesters Grb2 and inhibits the Ras-Erk pathway downstream of protein-tyrosine kinases". Genes Cells 11 (2): 143–51. doi:10.1111/j.1365-2443.2006.00926.x. PMID 16436051.
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