DRG1
Developmentally regulated GTP binding protein 1 | |||||||||||||
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Identifiers | |||||||||||||
Symbols | DRG1 ; NEDD3 | ||||||||||||
External IDs | OMIM: 603952 MGI: 1343297 HomoloGene: 3060 GeneCards: DRG1 Gene | ||||||||||||
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Orthologs | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | 4733 | 13494 | |||||||||||
Ensembl | ENSG00000185721 | ENSMUSG00000020457 | |||||||||||
UniProt | Q9Y295 | P32233 | |||||||||||
RefSeq (mRNA) | NM_004147 | NM_007879 | |||||||||||
RefSeq (protein) | NP_004138 | NP_031905 | |||||||||||
Location (UCSC) |
Chr 22: 31.4 – 31.53 Mb |
Chr 11: 3.19 – 3.27 Mb | |||||||||||
PubMed search | |||||||||||||
Developmentally-regulated GTP-binding protein 1 is a protein that in humans is encoded by the DRG1 gene.[1][2][3]
References
- ↑ Schenker T, Lach C, Kessler B, Calderara S, Trueb B (Nov 1994). "A novel GTP-binding protein which is selectively repressed in SV40 transformed fibroblasts". J Biol Chem 269 (41): 25447–53. PMID 7929244.
- ↑ Sazuka T, Tomooka Y, Ikawa Y, Noda M, Kumar S (Dec 1992). "DRG: a novel developmentally regulated GTP-binding protein". Biochem Biophys Res Commun 189 (1): 363–70. doi:10.1016/0006-291X(92)91567-A. PMID 1449490.
- ↑ "Entrez Gene: DRG1 developmentally regulated GTP binding protein 1".
Further reading
- Sazuka T, Kinoshita M, Tomooka Y; et al. (1992). "Expression of DRG during murine embryonic development.". Biochem. Biophys. Res. Commun. 189 (1): 371–7. doi:10.1016/0006-291X(92)91568-B. PMID 1280421.
- Mahajan MA, Park ST, Sun XH (1996). "Association of a novel GTP binding protein, DRG, with TAL oncogenic proteins.". Oncogene 12 (11): 2343–50. PMID 8649774.
- Zhao XF, Aplan PD (1999). "SCL binds the human homologue of DRG in vivo.". Biochim. Biophys. Acta 1448 (1): 109–14. doi:10.1016/s0167-4889(98)00129-3. PMID 9824680.
- Dunham I, Shimizu N, Roe BA; et al. (1999). "The DNA sequence of human chromosome 22.". Nature 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
- Li B, Trueb B (2000). "DRG represents a family of two closely related GTP-binding proteins.". Biochim. Biophys. Acta 1491 (1–3): 196–204. doi:10.1016/s0167-4781(00)00025-7. PMID 10760581.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Bandyopadhyay S, Pai SK, Gross SC; et al. (2003). "The Drg-1 gene suppresses tumor metastasis in prostate cancer". Cancer Res. 63 (8): 1731–6. PMID 12702552.
- Bandyopadhyay S, Pai SK, Hirota S; et al. (2004). "Role of the putative tumor metastasis suppressor gene Drg-1 in breast cancer progression". Oncogene 23 (33): 5675–81. doi:10.1038/sj.onc.1207734. PMID 15184886.
- Collins JE, Wright CL, Edwards CA; et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Bandyopadhyay S, Wang Y, Zhan R; et al. (2007). "The tumor metastasis suppressor gene Drg-1 down-regulates the expression of activating transcription factor 3 in prostate cancer". Cancer Res. 66 (24): 11983–90. doi:10.1158/0008-5472.CAN-06-0943. PMID 17178897.
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