DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase

DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase (EC 2.6.1.90, dTDP-6-deoxy-D-xylohex-3-uloseaminase, FdtB, TDP-3-keto-6-deoxy-D-galactose-3-aminotransferase, RavAMT, TDP-3-keto-6-deoxy-D-galactose 3-aminotransferase, TDP-3-dehydro-6-deoxy-D-galactose 3-aminotransferase) is an enzyme with systematic name dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose:2-oxoglutarate aminotransferase.^[1] This enzyme catalyses the following chemical reaction

dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2-oxoglutarate

\rightleftharpoons

dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose + L-glutamate

This enzyme is a pyridoxal-phosphate protein.

References

↑ Pfoestl, A., Hofinger, A., Kosma, P. and Messner, P. (2003). "Biosynthesis of dTDP-3-acetamido-3,6-dideoxy-α-D-galactose in Aneurinibacillus thermoaerophilus L420-91^T". J. Biol. Chem. 278: 26410–26417. doi:10.1074/jbc.m300858200. PMID 12740380.

External links

DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase at the US National Library of Medicine Medical Subject Headings (MeSH)

Transferase: nitrogenous groups (EC 2.6)

2.6.1: Transaminases	Aspartate transaminase GOT1 GOT2 Alanine transaminase GABA transaminase Tyrosine aminotransferase Ornithine aminotransferase Branched chain aminotransferase Alanine—glyoxylate transaminase AGXT

2.6.3: Oximinotransferases	Oximinotransferase

2.6.99: Other	Pyridoxine 5'-phosphate synthase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

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