DYNC1LI2

Dynein, cytoplasmic 1, light intermediate chain 2
Identifiers
Symbols	DYNC1LI2 ; DNCLI2; LIC2
External IDs	OMIM: 611406 MGI: 107738 HomoloGene: 4474 GeneCards: DYNC1LI2 Gene
Gene ontology Molecular function • microtubule motor activity • ATP binding Cellular component • centrosome • cytosol • cytoplasmic dynein complex • microtubule • membrane Biological process • microtubule cytoskeleton organization • transport • microtubule-based movement • metabolic process • antigen processing and presentation of exogenous peptide antigen via MHC class II • centrosome localization Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1783	234663
Ensembl	ENSG00000135720	ENSMUSG00000035770
UniProt	O43237	Q6PDL0
RefSeq (mRNA)	NM_001286157	NM_001013380
RefSeq (protein)	NP_001273086	NP_001013398
Location (UCSC)	Chr 16: 66.72 – 66.75 Mb	Chr 8: 104.42 – 104.44 Mb
PubMed search

Cytoplasmic dynein 1 light intermediate chain 2 is a protein that in humans is encoded by the DYNC1LI2 gene.^[1][2]

References

1. Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB (Nov 2005). "Cytoplasmic dynein nomenclature". J Cell Biol 171 (3): 411–3. doi:10.1083/jcb.200508078. PMC 2171247. PMID 16260502.
2. "Entrez Gene: DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2".

Further reading

• Hughes SM, Vaughan KT, Herskovits JS, Vallee RB (1995). "Molecular analysis of a cytoplasmic dynein light intermediate chain reveals homology to a family of ATPases.". J. Cell. Sci. 108 (1): 17–24. PMID 7738094.
• Chagnon P, Michaud J, Mitchell G; et al. (2003). "A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis.". Am. J. Hum. Genet. 71 (6): 1443–9. doi:10.1086/344580. PMC 378590. PMID 12417987.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Beausoleil SA, Jedrychowski M, Schwartz D; et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Beausoleil SA, Villén J, Gerber SA; et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
• Olsen JV, Blagoev B, Gnad F; et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.