Damnacanthal

Damnacanthal
Chemical structure of damnacanthal
Names
IUPAC name
3-Hydroxy-1-methoxy-9,10-dioxoanthracene-2-carbaldehyde
Other names
3-Hydroxy-1-methoxyanthraquinone-2-aldehyde
Identifiers
477-84-9 N
ChEMBL ChEMBL212948 YesY
ChemSpider 2843 YesY
Jmol interactive 3D Image
PubChem 2948
Properties
C16H10O5
Molar mass 282.25 g·mol−1
Density 1.461 g/mL
Boiling point 532 °C (990 °F; 805 K)
Related compounds
Related arylformaldehydes
Gossypol

Pyridoxal

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Damnacanthal is an anthraquinone which acts as a p56lck tyrosine kinase inhibitor.[1] It can be extracted from Morinda citrifolia.[2]

References

  1. Faltynek CR, Schroeder J, Mauvais P; et al. (September 1995). "Damnacanthal is a highly potent, selective inhibitor of p56lck tyrosine kinase activity". Biochemistry 34 (38): 12404–10. doi:10.1021/bi00038a038. PMID 7547985.
  2. Anekpankul T, Goto M, Sasaki M; et al. (July 2007). "Extraction of anti-cancer damnacanthal from roots of Morinda citrifolia by subcritical water". Separation and Purification Technology 55 (3): 343–349. doi:10.1016/j.seppur.2007.01.004.
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