Daniel Choquet

Daniel Choquet

Daniel Choquet, 2011
Born (1962-04-23) 23 April 1962
Paris, France
Residence France
Nationality French
Fields Neuroscience
Institutions CNRS and others

Daniel Choquet (born 1962) is a French neuroscientist.

Personal life and career

Daniel Choquet is the son of the physicist Yvonne Choquet-Bruhat and the mathematician Gustave Choquet. He is the grandson of the physicist Georges Bruhat. He obtained his bachelor's degree in 1979, followed by a degree in bioengineering from École centrale Paris in 1984. He obtained his P.hD. in 1988 from Pierre and Marie Curie University and studied pharmacology at the Pasteur Institute. That year, he started working for the French National Centre for Scientific Research (CNRS). From 1994 to 1996, he was a post-doctoral fellow at Duke University. The following year, in 1997, he was promoted to research director at the CNRS. He is the director of the Bordeaux Imaging Center[1] and the Interdisciplinary Institute for Neuroscience.[2] He was elected as a member of the French Academy of Sciences on November 30, 2010.[3]

Research

Choquet is a biologist, focusing on nanoscopic imaging and the organization of receptors in neurons. His early research included work on the properties of ion channels of B lymphocytes. This research work earned him the CNRS Bronze medal in 1990. During his post-doc at Duke, he discovered that cells can respond and adapt to the mechanical properties of their environment.[4]

Since 1996, he has researched the fundamental properties of the transmission of nerve impulses in the brain and developed new nanoscale imaging techniques. He discovered that receptors move in living neurons[5][6] and that these movements in and out synapses participate to synaptic plasticity,[7] a phenomenon thought to underlie learning and memory. Choquet's current work involves attempting to understand the role of receptor movements in neurodegenerative diseases. His recent research work has earned him the 2004 CEA Prize and the 2009 CNRS Silver medal.[8]

Awards

References

  1. ↑ "web site of the Bordeaux Imaging Center". Université de Bordeaux Segalen. 2011.
  2. ↑ "Site internet de l'Institut Interdisciplinaire de Neurosciences". Université de Bordeaux Segalen. 2011.
  3. ↑ "web site of the Academy of Sciences". April 2012.
  4. ↑ Choquet, D., Felsenfeld, D.P., Sheetz, M.P., and M-397 (1997). Extracellular matrix rigidity causes strengthening of integrin-cytoskeleton linkages. Cell 88, 39-48.
  5. ↑ Meier, J., Vannier, C., Serge, A., Triller, A., Choquet, D., and M-247 (2001). Fast and reversible trapping of surface glycine receptors by gephyrin. Nature Neuroscience 4, 253-260
  6. ↑ Borgdorff, A.J., and Choquet, D. (2002). Regulation of AMPA receptor lateral movements. Nature 417, 649-653.
  7. ↑ Heine, M., Groc, L., Frischknecht, R., Beique, J.C., Lounis, B., Rumbaugh, G., Huganir, R.L., Cognet, L., and Choquet, D. (2008). Surface mobility of postsynaptic AMPARs tunes synaptic transmission. Science 320, 201-205.
  8. ↑ text presented on Daniel Choquet at the awarding of the [silver medal http://www.cnrs.fr/fr/recherche/prix/docs/argent2009/ChoquetD.pdf]
  9. ↑ "Présentation des prix 2004 de l'académie des sciences" (PDF). site de l'académie des sciences. 2012.
  10. ↑ "Presentation of the Silver medal 2009" (PDF). web site of the CNRS. 2011.
  11. ↑ "Presentation of the 2011 Laureates of the "victoires de la médecine"". 2011.

External links

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