Deacetylisoipecoside synthase

deacetylisoipecoside synthase
Identifiers
EC number	4.3.3.3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a deacetylisoipecoside synthase (EC 4.3.3.3) is an enzyme that catalyzes the chemical reaction

deacetylisoipecoside + H₂O $\rightleftharpoons$ dopamine + secologanin

Thus, the two substrates of this enzyme are deacetylisoipecoside and H₂O, whereas its two products are dopamine and secologanin.

This enzyme belongs to the family of lyases, specifically amine lyases, which cleave carbon-nitrogen bonds. The systematic name of this enzyme class is deacetylisoipecoside dopamine-lyase (secologanin-forming). This enzyme is also called deacetylisoipecoside dopamine-lyase. This enzyme participates in indole and ipecac alkaloid biosynthesis.

References

• MH (1997). "Enzymatic condensation of dopamine and secologanin by cell-free extracts of Alangium lamarckii". Phytochemistry 45 (3): 477–484. doi:10.1016/S0031-9422(96)00828-X.