Dehydrocorybulbine

Dehydrocorybulbine
Names
IUPAC name
3-Hydroxy-2,9,10-trimethoxy-13-methyl-5,6-dihydroisoquinolino[3,2-a]isoquinolinium
Identifiers
ChemSpider 4475496
Jmol interactive 3D Image
PubChem 5316439
Properties
C21H22NO4+
Molar mass 352.40 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Dehydrocorybulbine (DHCB) is an alkaloid isolated from Corydalis yanhusuo.[1] Dehydrocorybulbine binds to the dopamine D1 receptor.[1]

Research has indicated that DHCB can be helpful in reducing neuropathic pain.[2][3]

References

  1. 1 2 Ma, ZZ; Xu, W; Jensen, NH; Roth, BL; Liu-Chen, LY; Lee, DY (2008). "Isoquinoline alkaloids isolated from Corydalis yanhusuo and their binding affinities at the dopamine D1 receptor". Molecules (Basel, Switzerland) 13 (9): 2303–12. PMID 18830156.
  2. Chinese herbal compound relieves inflammatory and neuropathic pain
  3. A Novel Analgesic Isolated from a Traditional Chinese Medicine. Current Biology. Volume 24, Issue 2, p117–123, 20 January 2014


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