Demetrios Spandidos

Demetrios A. Spandidos
Born (1947-04-13) April 13, 1947
Agios Konstantinos, Sparta, Greece
Fields Oncology, virology
Institutions University of Crete
Alma mater Aristotle University of Thessaloniki, McGill University, University of Glasgow
Thesis Genetics and transcription of reovirus (1976)
Spouse Panayota D. Krempeniou
Children Two

Demetrios A. Spandidos is a Greek virologist and cancer researcher. He has been professor of virology at the University of Crete since 1989. He is also the founder and editor-in-chief of four medical journals: the International Journal of Oncology, Oncology Reports, the International Journal of Molecular Medicine, and Molecular Medicine Reports.

Education

Spandidos received his bachelor's degree from the University of Thessaloniki in 1971, his PhD from McGill University in 1976, and a DSc from the University of Glasgow in 1989.[1]

Career

From 1976 to 1978, Spandidos worked as a postdoctoral fellow at the University of Toronto, working in the laboratory of Louis Siminovitch.[2] In 1978, Spandidos gave a presentation to a Dana Farber Cancer Institute seminar. In this presentation, Spandidos claimed to have proven that oncogenes were the root cause of all cancers. Robert Weinberg, a professor at the Massachusetts Institute of Technology, was in the audience when Spandidos gave this talk, and later recalled that he had devised what he called "exactly the same" strategy to identify oncogenes in human tumors not long before Spandidos' talk.[3] Spandidos had published these findings in Cell a month prior to Weinberg having his idea, which, like Spandidos' paper, related to transfectable oncogenes.[4]

Spandidos was forced to end his position at the University of Toronto in Siminovitch's laboratory due to accusations of fraud.[5] Two postdocs in Siminovitch lab were unable to reproduce Spandidos' findings, and Spandidos did not present the raw data proving that he was innocent.[5] Unfortunately, Siminovitch did not initiate an independent investigation and the accusations have never been officially confirmed.[5]

From 1978 to 1979 Spandidos was an assistant professor at the Hellenic Anticancer Institute in Athens, Greece.[2] From 1979 to 1989, Spandidos worked at the Beatson Institute for Cancer Research, where he studied the ras oncogene.[2][6]

In 1992, Spandidos established Spandidos Publications, a publisher of scientific journals. It currently publishes eight journals: International Journal of Molecular Medicine, International Journal of Oncology, Molecular Medicine Reports, Oncology Reports, Experimental and Therapeutic Medicine, Oncology Letters, Biomedical Reports, and Molecular and Clinical Oncology.[7] None of the journals are registered in the Committee on Publication Ethics (COPE).[8]

References

  1. "Spandidos Lab Home Page, University of Crete.".
  2. 1 2 3 Spandidos, Demetrios A. (November 2004). "The Cancer Story" (PDF). Cancer Biology and Therapy 3 (11): 1184–1186.
  3. Warsh, David (7 October 1996). "Nobel Contender Called Out On Strikes Not Even His Own". Chicago Tribune. Retrieved 31 December 2014.
  4. Angier, Natalie (2014). Natural Obsessions: Striving to Unlock the Deepest Secrets of the Cancer Cell. Houghton Mifflin Harcourt. p. 79.
  5. 1 2 3 Angier, Natalie (2014). Natural Obsessions: Striving to Unlock the Deepest Secrets of the Cancer Cell. Houghton Mifflin Harcourt. pp. 85–89.
  6. Bartels, Ditta (July 1987). "Escape of the Cancer Genes?". New Scientist (1571): 53.
  7. "About Spandidos Publications". Spandidos Publications. Retrieved 7 January 2015.
  8. "Committee on Publication Ethics: COPE | Raising the Quality of Academic Journals". publicationethics.org. Retrieved 2015-12-29.

External links

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