Deslanoside

"Cedilanide" redirects here. It is not to be confused with Cedilanid, a trade name of lanatoside C.

Deslanoside
Systematic (IUPAC) name

(3β,5β,12β)-3-[(O-β-D-glucopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	17598-65-1^Y
ATC code	C01AA07 (WHO)
PubChem	CID 28620
IUPHAR/BPS	6806
DrugBank	DB01078^Y
ChemSpider	26618^Y
UNII	YGY317RK75^Y
KEGG	D01240^Y
ChEBI	CHEBI:31468^Y
ChEMBL	CHEMBL1614^Y
Chemical data
Formula	C₄₇H₇₄O₁₉
Molar mass	943.08 g/mol
InChI InChI=1S/C47H74O19/c1-20-41(64-36-16-30(50)42(21(2)60-36)65-37-17-31(51)43(22(3)61-37)66-44-40(56)39(55)38(54)32(18-48)63-44)29(49)15-35(59-20)62-25-8-10-45(4)24(13-25)6-7-27-28(45)14-33(52)46(5)26(9-11-47(27,46)57)23-12-34(53)58-19-23/h12,20-22,24-33,35-44,48-52,54-57H,6-11,13-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27-,28+,29+,30+,31+,32-,33-,35+,36+,37+,38-,39+,40-,41-,42-,43-,44+,45+,46+,47+/m1/s1^Y Key:OBATZBGFDSVCJD-LALPQLPRSA-N^Y
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Deslanoside (trade name Cedilanide in Brazil^[1]) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). It is found in the leaves of Digitalis lanata, the Woolly Foxglove.^[2]^[3]

References

↑ Drugs.com: Cedilanide
↑ Bakke, O. M.; Aslaksen, A.; Lehmann, V.; Lien, E. (1981). "Pharmacokinetics and serum concentration--effect relationship of intravenous deslanoside". Journal of cardiovascular pharmacology 3 (5): 1015–1025. doi:10.1097/00005344-198109000-00012. PMID 6168847.
↑ Budavari, Susan, ed. (1996), The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals (12th ed.), Merck, ISBN 0911910123 , 2967

Cardiac glycosides (C01A)

Bufadienolides

Bufo	Arenobufagin Bufotalin Cinobufagin Marinobufagin

Scilla	Proscillaridin Scilliroside

Cardenolides

Digitalis	Acetyldigitoxin Acetyldigoxin Digitoxin^# Digoxin^# Lanatoside C Deslanoside Metildigoxin Gitoformate

Kalanchoe	Daigremontianin

Strophanthus	Ouabain (g-Strophanthin) k-Strophanthin Cymarin

Thevetia	Peruvoside

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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