Diaminopropionate ammonia-lyase

diaminopropionate ammonia-lyase
Identifiers
EC number	4.3.1.15
CAS number	51901-19-0
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a diaminopropionate ammonia-lyase (EC 4.3.1.15) is an enzyme that catalyzes the chemical reaction

2,3-diaminopropanoate + H₂O $\rightleftharpoons$ pyruvate + 2 NH₃

Thus, the two substrates of this enzyme are 2,3-diaminopropionate and H₂O, whereas its two products are pyruvate and NH₃.

This enzyme belongs to the family of lyases, specifically ammonia lyases, which cleave carbon-nitrogen bonds. The systematic name of this enzyme class is 2,3-diaminopropanoate ammonia-lyase (adding H₂O; pyruvate-forming). Other names in common use include diaminopropionatase, alpha,beta-diaminopropionate ammonia-lyase, 2,3-diaminopropionate ammonia-lyase, and 2,3-diaminopropanoate ammonia-lyase. It employs one cofactor, pyridoxal phosphate.

References

• Nagasawa T, Tanizawa K, Satoda T, Yamada H (1988). "Diaminopropionate ammonia-lyase from Salmonella typhimurium Purification and characterization of the crystalline enzyme, and sequence determination of the pyridoxal 5'-phosphate binding peptide". J. Biol. Chem. 263 (2): 958–64. PMID 3275662.