Diethylamino hydroxybenzoyl hexyl benzoate

Diethylamino hydroxybenzoyl hexyl benzoate
Names

IUPAC name Hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate
Other names Uvinul A Plus
Identifiers
CAS Number	302776-68-7^Y
ChemSpider	8286957^Y
Jmol interactive 3D	Image Image
PubChem	10111431
InChI InChI=1S/C24H31NO4/c1-4-7-8-11-16-29-24(28)20-13-10-9-12-19(20)23(27)21-15-14-18(17-22(21)26)25(5-2)6-3/h9-10,12-15,17,26H,4-8,11,16H2,1-3H3^Y Key: FDATWRLUYRHCJE-UHFFFAOYSA-N^Y InChI=1/C24H31NO4/c1-4-7-8-11-16-29-24(28)20-13-10-9-12-19(20)23(27)21-15-14-18(17-22(21)26)25(5-2)6-3/h9-10,12-15,17,26H,4-8,11,16H2,1-3H3 Key: FDATWRLUYRHCJE-UHFFFAOYAR
SMILES CCCCCCOC(=O)C1=CC=CC=C1C(=O)C2=C(C(=CC=C2)N(CC)CC)O O=C(c1ccc(cc1O)N(CC)CC)c2ccccc2C(=O)OCCCCCC
Properties
Chemical formula	C₂₄H₃₁NO₄
Molar mass	397.51 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is ^YN ?)
Infobox references

Diethylamino hydroxybenzoyl hexyl benzoate (INCI) is an organic compound used in sunscreens to absorb UVA radiation. It is marketed as Uvinul A Plus by BASF. DHHB has an absorption maximum of 354 nm.^[1]^[2]

DHHB has excellent photostability and compatibility with other UV absorbers and other cosmetic ingredients.^[3]

DHHB has been approved for the use in sunscreens in the European Union since 2005 with a maximum of 10 per cent^[4]^[5] and is also approved in South America, Mexico, Japan and Taiwan.^[6] In the United States it can be used for product protection.^[7]

References

↑ Vielhaber G, Grether-Beck S, Koch O, Johncock W, Krutmann J (March 2006). "Sunscreens with an absorption maximum of > or =360 nm provide optimal protection against UVA1-induced expression of matrix metalloproteinase-1, interleukin-1, and interleukin-6 in human dermal fibroblasts". Photochem Photobiol Sci 5 (3): 275–82. doi:10.1039/b516702g. PMID 16520862.
↑ UV Absorber Portfolio Performance Data and Regulatory Status, cosmetics.basf.de
↑ http://sciencelinks.jp/j-east/article/200216/000020021602A0553728.php
↑ http://www.corporate.basf.com/en/investor/strategie/kunden/uvinul.htm
↑ http://eur-lex.europa.eu/LexUriServ/site/en/consleg/1976/L/01976L0768-20060809-en.pdf
↑ http://www.cosmetics.basf.de/pdf/publications/Uvinul_A_Plus_Broschuere.pdf
↑ http://www2.basf.us/corporate/news2004/02272004b.htm

Sunscreening agents approved by the US FDA or other agencies

UVA: 400–315 nm UVB: 315–290 nm chemical agents unless otherwise noted

UVA filters	Avobenzone (Parsol 1789) Bisdisulizole disodium (Neo Heliopan AP) Diethylamino hydroxybenzoyl hexyl benzoate (Uvinul A Plus) Ecamsule (Mexoryl SX) Menthyl anthranilate

UVB filters	Amiloxate 4-Aminobenzoic acid (PABA) Cinoxate Ethylhexyl triazone (Uvinul T 150) Homosalate 4-Methylbenzylidene camphor (Parsol 5000) Octyl methoxycinnamate (Octinoxate) Octyl salicylate (Octisalate) Padimate O (Escalol 507) Phenylbenzimidazole sulfonic acid (Ensulizole) Polysilicone-15 (Parsol SLX) Trolamine salicylate

UVA+UVB filters	Bemotrizinol (Tinosorb S) Benzophenones 1–12 Dioxybenzone Drometrizole trisiloxane (Mexoryl XL) Iscotrizinol (Uvasorb HEB) Octocrylene Oxybenzone (Eusolex 4360) Sulisobenzone hybrid (chemical/physical): Bisoctrizole (Tinosorb M) physical: Titanium dioxide Zinc oxide

See also: Photoprotection Potential health risks of sunscreen Sun protective clothing Sun tanning Sunburn

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