Donovan's solution

Donovan's Solution

Names
IUPAC name iodomercury; triiodoarsane
Other names liquor hydriodatis arsenici et hydrargyri
Identifiers
CAS Number	8012-54-2
ChemSpider	29291736
Jmol interactive 3D	Image
PubChem	24679
RTECS number	CG3200000
UN number	1557
InChI InChI=1S/AsI3.Hg.HI/c2-1(3)4;;/h;;1H/q;+1;/p-1 Key: QLULWSBMTZWVDE-UHFFFAOYSA-M
SMILES [As](I)(I)I.I[Hg]
Properties
Chemical formula	AsHgI4
Molar mass	783.12948
Appearance	Clear, colourless, or pale yellow. Darkens with age.
Boiling point	403 °C (757 °F; 676 K) at 760 mmHg
Solubility in water	Yes
Hazards
Main hazards	Toxic
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Donovan's solution is an inorganic compound prepared from arsenic triiodide and mercuric iodine.^[1]

Method

1g each of AsI₃ and HgI₂ with 0.9 sodium bicarbonate in water to make 100 ml.

Cooley's cyclopædia of practical receipts and ... information on the arts, manufactures, and trades gives a more complex method.^[2]

Uses

Has been used in veterinary medicine to treat chronic diseases of the skin.^[3] Also as a folk remedy.^[4] Used during the 19th century to treat Lepra vulgaris^[5] and psoriasis^[6][7] in humans, taken internally.

References

1. Budavari, Susan (1989). "3413. Donovan's Solution". The Merck Index (11th ed.). Merck & Co., Inc. p. 537. ISBN 091191028X. LCCN 89060001.
2. Arnold James Cooley (1880). "Solution". In Richard Vine Tuson. A cyclopædia of practical receipts and ... information on the arts, manufactures, and trades II (6th ed.). p. 1525.
3. Oxtoby, David W.; H.P. Gillis; Allan Campion (2012). Principles of modern chemistry (7th ed.). Belmont, Calif.: Brooks/Cole Cengage Learning. p. 513. ISBN 0840049315.
4. "Donovan's solution". Chemical Dictionary Online. Retrieved 29 November 2013.
5. Sir Erasmus Wilson (1847). "Treatment of Lepra". On Diseases of the Skin (2nd ed.). John Churchill. p. 271.
6. Henry G. Piffard (1881). "Psoriasis Treatment. Part 6". A Treatise On The Materia Medica And Therapeutics Of The Skin. Sampson, Low, Marston, Searle & Rivington. p. 254.
7. "GOOD RESULTS OF DONOVAN'S SOLUTION IN PSORIASIS.". The Lancet 70 (1770): 116. August 1857. doi:10.1016/S0140-6736(02)38789-0.

External links