Ductal cells

Ductal cells refer to cells lining the pancreatic duct and are responsible for production of bicarbonate-rich secretion. Ductal cells are stimulated by the hormone secretin and are responsible for maintenance of the duodenal pH and prevention of duodenal injury from acidic chyme. Ductal cell mix their production with acinar cells' to make up the pancreatic juice.

Physiology of the gastrointestinal system

GI tract

Upper

Exocrine	Chief cells Pepsinogen Parietal cells Gastric acid Intrinsic factor Foveolar cells HCO₃⁻ Mucus Goblet cells Mucus

Processes	Swallowing Vomiting

Fluids	Saliva Gastric acid

Lower

Enteric nervous system

Endocrine/paracrine

G cells gastrin D cells somatostatin ECL cells Histamine

enterogastrone:	I cells CCK K cells GIP S cells secretin

Enteroendocrine cells Enterochromaffin cell APUD cell

Fluids

Intestinal juice

Processes

Either/both

Processes	Peristalsis (Interstitial cell of Cajal Basal electrical rhythm) Gastrocolic reflex Digestion

Accessory

Fluids	Bile Pancreatic juice

Processes	Enterohepatic circulation

Abdominopelvic

Peritoneal fluid

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