Dupracetam

Dupracetam

Systematic (IUPAC) name
2-(2-oxopyrrolidin-1-yl)-N'-[2-(2-oxopyrrolidin-1-yl)acetyl]acetohydrazide
Clinical data
Legal status	Unscheduled
Identifiers
CAS Number	59776-90-8
ATC code	none
PubChem	CID 68793
ChemSpider	62033
UNII	BVM2UGN450
ChEMBL	CHEMBL2104359
Chemical data
Formula	C12H18N4O4
Molar mass	282.296 g/mol
SMILES C1CC(=O)N(C1)CC(=O)NNC(=O)CN2CCCC2=O
InChI InChI=1S/C12H18N4O4/c17-9(7-15-5-1-3-11(15)19)13-14-10(18)8-16-6-2-4-12(16)20/h1-8H2,(H,13,17)(H,14,18) Key:YPUPYVWSTBYCBY-UHFFFAOYSA-N
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Dupracetam is a nootropic drug from the racetam family.^[1][2]

One of its metabolites, 1-Methylhydantoin, displays renal toxicity in high doses.^[3]

See also

• Piracetam

References

1. Dell HD, Jacobi H, Kamp R, Kurz J, Wünsche C (August 1981). "[1-Methylhydantoin, an unexpected metabolite of the intelligence-affecting substance dupracetam (author's transl)]". Archiv der Pharmazie (in German) 314 (8): 697–702. PMID 7294979.
2. Hall ED, Von Voigtlander PF (November 1987). "Facilitatory effects of piracetam on excitability of motor nerve terminals and neuromuscular transmission". Neuropharmacology 26 (11): 1573–9. doi:10.1016/0028-3908(87)90003-7. PMID 2829047.
3. Yang, B.; Liu, D.; Li, C.; Liu, F.; Peng, Y.; Jiang, Y. (2007). "1-Methylhydantoin Cytotoxicity on Renal Proximal Tubular Cells in Vitro". Renal Failure 29 (8): 1025–1029. doi:10.1080/08860220701641272. PMID 18067051.