Etidocaine

Etidocaine
Systematic (IUPAC) name

N-(2,6-dimethylphenyl)- 2-(ethyl(propyl)amino)butanamide
Clinical data
Trade names	Duranest
AHFS/Drugs.com	Micromedex Detailed Consumer Information
MedlinePlus	a603026
Pregnancy category	AU: B1 US: B (No risk in non-human studies)
Routes of administration	Parenteral
Legal status
Legal status	US: ℞-only
Pharmacokinetic data
Bioavailability	n/a
Metabolism	Hepatic
Biological half-life	2.5 hours
Excretion	Renal
Identifiers
CAS Number	36637-18-0^N
ATC code	N01BB07 (WHO)
PubChem	CID 37497
IUPHAR/BPS	2621
DrugBank	DB08987^N
ChemSpider	34400^Y
UNII	I6CQM0F31V^Y
KEGG	D04095^Y
ChEBI	CHEBI:4904^Y
ChEMBL	CHEMBL492^Y
Chemical data
Formula	C₁₇H₂₈N₂O
Molar mass	276.42 g/mol
SMILES O=C(Nc1c(C)cccc1C)C(CC)N(CC)CCC
InChI InChI=1S/C17H28N2O/c1-6-12-19(8-3)15(7-2)17(20)18-16-13(4)10-9-11-14(16)5/h9-11,15H,6-8,12H2,1-5H3,(H,18,20)^Y Key:VTUSIVBDOCDNHS-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)

Etidocaine, marketed under the trade name Duranest, is a local anesthetic given by injection during surgical procedures and labor and delivery. Etidocaine has a long duration of activity, and the main disadvantage of using during dentistry is increased bleeding during surgery.^[1]

References

↑ Sisk, A. L. (1992). "Long-acting local anesthetics in dentistry". Anesthesia Progress 39 (3): 53–60. PMC 2148750. PMID 1308373.

External links

Duranest (RxList)

Local anesthetics (primarily sodium channel blockers) (N01B)

Esters by acid

Aminobenzoic	Benzocaine Butacaine Butamben Chloroprocaine Dimethocaine Lucaine Meprylcaine Metabutethamine Metabutoxycaine Orthocaine Propoxycaine Procaine (Novocaine) Proxymetacaine Risocaine Tetracaine

Benzoic	Amylocaine Cocaine Cyclomethycaine α-Eucaine β-Eucaine Hexylcaine Isobucaine Piperocaine

ArCO2- (not para-amino or Ph)	Amoproxan (3,4,5-Trimethoxybenzoyl) 3-(p-Fluorobenzoyloxy)tropane

Amides

Articaine
Bupivacaine # / Levobupivacaine / Ropivacaine
Butanilicaine
Carticaine
Dibucaine
Etidocaine
Lidocaine #
Mepivacaine
Prilocaine
Trimecaine

Combinations

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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