EPS8L3
| EPS8-like 3 | |||||||||||||
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PDB rendering based on 1wxt. | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | EPS8L3 ; EPS8R3 | ||||||||||||
| External IDs | OMIM: 614989 MGI: 2139743 HomoloGene: 15878 GeneCards: EPS8L3 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 79574 | 99662 | |||||||||||
| Ensembl | ENSG00000198758 | ENSMUSG00000040600 | |||||||||||
| UniProt | Q8TE67 | Q91WL0 | |||||||||||
| RefSeq (mRNA) | NM_024526 | NM_133867 | |||||||||||
| RefSeq (protein) | NP_078802 | NP_598628 | |||||||||||
| Location (UCSC) |
Chr 1: 109.75 – 109.76 Mb |
Chr 3: 107.88 – 107.89 Mb | |||||||||||
| PubMed search | |||||||||||||
Epidermal growth factor receptor kinase substrate 8-like protein 3 is an enzyme that in humans is encoded by the EPS8L3 gene.[1][2]
This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Alternatively spliced transcript variants encoding different isoforms exist.[2]
References
- ↑ Tocchetti A, Confalonieri S, Scita G, Di Fiore PP, Betsholtz C (Mar 2003). "In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure". Genomics 81 (2): 234–44. doi:10.1016/S0888-7543(03)00002-8. PMID 12620401.
- 1 2 "Entrez Gene: EPS8L3 EPS8-like 3".
Further reading
- Gregory SG, Barlow KF, McLay KE; et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Offenhäuser N, Borgonovo A, Disanza A; et al. (2004). "The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathway.". Mol. Biol. Cell 15 (1): 91–8. doi:10.1091/mbc.E03-06-0427. PMC 307530. PMID 14565974.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
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