ETV7

Ets variant 7
Identifiers
Symbols	ETV7 ; TEL-2; TEL2; TELB
External IDs	OMIM: 605255 HomoloGene: 56746 GeneCards: ETV7 Gene
Gene ontology Molecular function • RNA polymerase II regulatory region sequence-specific DNA binding • transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding • protein binding Cellular component • nucleus • nucleoplasm Biological process • negative regulation of transcription from RNA polymerase II promoter • transcription from RNA polymerase II promoter • organ morphogenesis • cell differentiation Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	51513	n/a
Ensembl	ENSG00000010030	n/a
UniProt	Q9Y603	n/a
RefSeq (mRNA)	NM_001207035	n/a
RefSeq (protein)	NP_001193964	n/a
Location (UCSC)	Chr 6: 36.35 – 36.39 Mb	n/a
PubMed search		n/a

Transcription factor ETV7 is a protein that in humans is encoded by the ETV7 gene.^[1][2][3]

References

1. Potter MD, Buijs A, Kreider B, van Rompaey L, Grosveld GC (Jun 2000). "Identification and characterization of a new human ETS-family transcription factor, TEL2, that is expressed in hematopoietic tissues and can associate with TEL1/ETV6". Blood 95 (11): 3341–8. PMID 10828014.
2. Gu X, Shin BH, Akbarali Y, Weiss A, Boltax J, Oettgen P, Libermann TA (Mar 2001). "Tel-2 is a novel transcriptional repressor related to the Ets factor Tel/ETV-6". J Biol Chem 276 (12): 9421–36. doi:10.1074/jbc.M010070200. PMID 11108721.
3. "Entrez Gene: ETV7 ets variant gene 7 (TEL2 oncogene)".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Poirel H, Lopez RG, Lacronique V; et al. (2000). "Characterization of a novel ETS gene, TELB, encoding a protein structurally and functionally related to TEL". Oncogene 19 (41): 4802–6. doi:10.1038/sj.onc.1203830. PMID 11032031.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Boccuni P, MacGrogan D, Scandura JM, Nimer SD (2003). "The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6)". J. Biol. Chem. 278 (17): 15412–20. doi:10.1074/jbc.M300592200. PMID 12588862.
• Mungall AJ, Palmer SA, Sims SK; et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Cardone M, Kandilci A, Carella C; et al. (2005). "The Novel ETS Factor TEL2 Cooperates with Myc in B Lymphomagenesis". Mol. Cell. Biol. 25 (6): 2395–405. doi:10.1128/MCB.25.6.2395-2405.2005. PMC 1061619. PMID 15743832.

External links

• Drosophila anterior open - The Interactive Fly