Elspeth McLachlan

Elspeth Mc Lachlan (born 22 July 1942) is a world authority on neural pathways within the autonomic nervous system. Her work has included detailed analyses of transmission in autonomic ganglia to studies of the organisation of autonomic nervous pathways and their disorder in pathological states, particularly injuries to peripheral nerves and the spinal cord.^[1]

McLachlan was born in Bowral, New South Wales, Australia.^[2]

Education

McLachlan was educated at the University of Sydney, from which institution she received Bachelor of Science degree in 1962, and a PhD in 1973, and a Doctor of Science degree in 1994.^[3]

Career

• 1985–1993 – Visiting Professor Christian-Albrechts-Universität zu Kiel Germany, Kiel ^[3]
• 1987–1988 – National Health and Medical Research Council Principal Research Fellow and Associate Professor with the School of Physiology and Pharmacology at the University of New South Wales
• 1988–1993 – Professor and Head of the Department of Physiology & Pharmacology at the University of Queensland
• 1993–2011 – Senior Principal Research Fellow at the Prince of Wales Medical Research Institute Randwick Australia
• 1997 – Fellow of the Australian Academy of Science (Science 2008) ^[4]
• 1999–2001 – Executive Head National Health & Medical Research Council, Centre for Research Management Australia, Canberra
• 2000–2003 – Investigador Asociado Universidad Miguel Hernández de Elche, Instituto de Neurociencias Spain, Alicante
• 2001–2006 – Pro-Vice Chancellor (Research) and Research Professor University of New South Wales Australia, Kensington
• 2007–present – Emeritus Professor University of New South Wales, Neuroscience Research Australia Australia, Kensington
• 2008–2014 – Honorary Research Fellow University of Glasgow, School of LIfe Science United Kingdom, Glasgow
• 2011–2014 – Honorary Senior Principal Research Fellow Neuroscience Research Australia, Australia, Sydney.^[3]

Awards

• Feb 2009 Award: Honorary Member, Australian Neuroscience Society
• Sep 2008 Award: Honorary Member, Australian Physiological Society
• Feb 2006 Award: Distinguished Achievement Award, Australian Neuroscience Society
• May 2003 Award: Centenary Medal for contribution to the Australian community and science in medical research
• 1999 Invitation Fellowship, Japan Society for the Promotion of Science (JSPS)
• Nov 1998 Award: Ramaciotti Medal for Excellence in Biomedical Research
• May 1997 Award: Elected Fellow, Australian Academy of Science ^[3]
• 1996 Invitation Fellowship, Japan Society for the Promotion of Science (JSPS)
• 1995 Orbeli Medal, Armenian Academy of Neuroscience
• Mar 1993 Award: Max-Planck-Research Prize (Max-Planck-Forschungspreis) for international collaborative research (with W. Jänig)

Selected publications

• McLachlan, E.M., Jänig, W., Devor, M. and Michaelis, M. (1993) Peripheral nerve injury triggers noradrenergic sprouting within dorsal root ganglia. Nature, Lond. 363, 543-546 ^[5]
• Jänig, W. and McLachlan, E.M. (1992) Characteristics of function-specific pathways in the sympathetic nervous system. Trends in Neurosciences 15, 475-481.^[6]
• Sah, P. and McLachlan, E.M. (1991) Calcium-activated K+ currents underlying the afterhyperpolarization in guinea pig vagal neurons: a role for calcium activated calcium release. Neuron 7, 257-264 ^[7]
• McLachlan, E.M. and Martin, A.R. (1981). Non-linear summation of end-plate potentials in the frog and mouse. J. Physiol. 311, 307-324 ^[8]
• Schmid, A.B., Coppieters, M.W., Ruitenberg, M.J. and McLachlan, E.M. (2013) Local and Remote Immune-Mediated Inflammation After Mild Peripheral Nerve Compression in Rats. Journal of neuropathology and experimental neurology 06/2013 ^[4]
• Diana Tripovic, Elspeth M McLachlan, James A Brock. Removal of half the sympathetic innervation does not reduce vasoconstrictor responses in rat tail artery. . Prince of Wales Medical Research Institute; The Journal of Physiology ^[4]
• Elspeth M. McLachlan, Ping Hu. Inflammation in Dorsal Root Ganglia After Peripheral Nerve Injury: Effects Of The Sympathetic Innervation. Neuroscience Research Australia, Randwick, NSW 2031, and the University of New South Wales, Sydney, NSW 2052, Australia Autonomic neuroscience: basic & clinical ^[4]
• Diana Tripovic, Svetlana Pianova, Elspeth M McLachlan, James A Brock. Slow and incomplete sympathetic reinnervation of rat tail artery restores the amplitude of nerve-evoked contractions provided a perivascular plexus is present. Prince of Wales Medical Research Institute, University of New South Wales, Randwick, New South Wales, Australia. AJP Heart and Circulatory Physiology ^[4]

References

1. "McLachlan, Elspeth M. (Elspeth Mary)". Trove. Encyclopedia of Australian Science. 2008. Retrieved 30 July 2014.
2. Walker, Rosanne. "McLachlan, Elspeth Mary (1942 - )". Encyclopedia of Aiustralian Science. Encyclopedia of Australian Science. Retrieved 31 July 2014.
3. Hofmayer, D. S.; Madisch, D. I. "Researchgate Profile - Elspeth Mclachlan". ResearchGate. ResearchGate GmbH. Retrieved 30 July 2014.
4. "McLachlan, Elspeth M. (Elspeth Mary)". Trove. Encyclopaedia of Australian Science. 2008. Retrieved 30 July 2014.
5. "Peripheral nerve injury triggers noradrenergic sprouting within dorsal root ganglia". Pubmed.gov. National Centre for Biotechnology Information. Retrieved 14 August 2014.
6. "Characteristics of function-specific pathways in the sympathetic nervous system". Trends in Neurosciences. Elsevier Inc. Retrieved 14 August 2014.
7. "Ca(2+)-activated K+ currents underlying the afterhyperpolarization in guinea pig vagal neurons: a role for Ca(2+)-activated Ca2+ release.". Pubmed.gov. National Centre for Biotechnology Information. Retrieved 14 August 2014.
8. McLachlan, Elspeth M; Martin, A. R. (1981). "NON-LINEAR SUMMATION OF END-PLATE POTENTIALS IN THE FROG AND MOUSE" (PDF). Journal of Physiology. Retrieved 14 August 2014.