Emperipolesis
In medicine, emperipolesis is the presence of an intact cell within the cytoplasm of another cell.[1] It is derived from Greek (em is inside, peri is around, polemai is wander about).[2]
It is related to peripolesis, which is the attachment of one cell to another.[3]
Associations
It is seen in various conditions including:
- Rosai-Dorfman disease[4]
- Autoimmune hepatitis
- Megakaryocytes containing segmented neutrophils passing through them as they migrate from the bone marrow.
- Leukocyte migration from the blood stream to tissues through endothelial cells, in a process also known as transcellular migration and is akin to diapedesis (paracellular migration).
Additional images
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Emperipolesis: a band neutrophil inside a megakaryocyte (Wright-Giemsa, 100x, oil).
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Emperipolesis in Rosai-Dorfman disease highlighted by S-100 staining.
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Emperipolesis: Megakaryocyte containing a segmented neutrophil, stained with a May-Grünwald Giemsa stain.
See also
References
- ↑ Emperipolesis. dictionary.com. URL: http://dictionary.reference.com/browse/emperipolesis. Accessed on: 11 August 2010.
- ↑ Emperipolesis. Stedman's Medical Dictionary. 27th Ed.
- ↑ Lyons DJ, Gautam A, Clark J, et al. (January 1992). "Lymphocyte macrophage interactions: peripolesis of human alveolar macrophages". Eur. Respir. J. 5 (1): 59–66. PMID 1577151.
- ↑ Demicco EG, Rosenberg AE, Björnsson J, Rybak LD, Unni KK, Nielsen GP (July 2010). "Primary Rosai-Dorfman Disease of Bone: A Clinicopathologic Study of 15 Cases". Am J Surg Pathol 34 (9): 1324–1333. doi:10.1097/PAS.0b013e3181ea50b2. PMID 20679880.
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