Endopeptidase La

Endopeptidase La
Identifiers
EC number	3.4.21.53
CAS number	79818-35-2
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Endopeptidase La (EC 3.4.21.53, ATP-dependent serine proteinase, lon proteinase, protease La, proteinase La, ATP-dependent lon proteinase, ATP-dependent protease La, Escherichia coli proteinase La, Escherichia coli serine proteinase La, gene lon protease, gene lon proteins, PIM1 protease, PIM1 proteinase, serine protease La) is an enzyme.^[1][2][3] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins in presence of ATP

This enzyme is a product of the lon gene in Escherichia coli.

References

1. Desautels, M. and Goldberg, A.L. (1982). "Demonstration of an ATP-dependent, vanadate-sensitive endoprotease in the matrix of rat liver mitochondria". J. Biol. Chem. 257: 11673–11679. PMID 6749845.
2. Larimore, F.S., Waxman, L. and Goldberg, A.L. (1982). "Studies of the ATP-dependent proteolytic enzyme, protease La, from Escherichia coli". J. Biol. Chem. 257: 4187–4195. PMID 7040380.
3. Chin, D.T., Goff, S.A., Webster, T., Smith, T. and Goldberg, A.L. (1988). "Sequence of the lon gene in Escherichia coli. A heat-shock gene which encodes the ATP-dependent protease La". J. Biol. Chem. 263: 11718–11728. PMID 3042779.

External links

• Endopeptidase La at the US National Library of Medicine Medical Subject Headings (MeSH)