Epomediol

Epomediol
Systematic (IUPAC) name


(1s,4r,6R,7S)-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane-6,7-diol
Identifiers
CAS Number	56084-15-2
ATC code	A05BA05
PubChem	CID 115056
ChemSpider	102967
Synonyms	1,3,3-Trimethyl-2-oxabicyclo [2.2.2]octane-6,7-endo,endo-diol
Chemical data
Formula	C₁₀H₁₈O₃
Molar mass	186.248 g/mol
SMILES OC1CC2C(OC1(C)C(O)C2)(C)C

Epomediol (trade name Clesidren) is a synthetic terpenoid with choleretic effects. It has been used in the symptomatic treatment of itching due to intrahepatic cholestasis of pregnancy.^[1]^[2]^[3]

References

↑ Gonzalez MC, Iglesias J, Tiribelli C; et al. (September 1992). "Epomediol ameliorates pruritus in patients with intrahepatic cholestasis of pregnancy". J Hepatol 16 (1-2): 241–2. doi:10.1016/S0168-8278(05)80122-9. PMID 1484159.
↑ Reyes H (December 1992). "The spectrum of liver and gastrointestinal disease seen in cholestasis of pregnancy". Gastroenterol Clin North Am 21 (4): 905–21. PMID 1478743.
↑ Reyes H, Simon FR (August 1993). "Intrahepatic cholestasis of pregnancy: an estrogen-related disease". Semin Liver Dis 13 (3): 289–301. doi:10.1055/s-2007-1007357. PMID 8235718.

Bile and liver therapy (A05)

Bile therapy	bile acid (Chenodeoxycholic acid Cholic acid Ursodeoxycholic acid) Obeticholic acid Nicotinyl methylamide Piprozolin Hymecromone Cyclobutyrol

Liver therapy	Arginine glutamate Silymarin Citiolone Epomediol Ornithine oxoglutarate Tidiacic arginine Glycyrrhizin

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