Exact Sciences (company)

Exact Sciences Corporation

Exact Sciences Corp. is a molecular diagnostics company with an initial focus on the early detection and prevention of colorectal cancer.[1] The company was founded in 1995 in Marlborough, Massachusetts and today is headquartered in Madison, Wisconsin.[2]

In August 2014, the U.S. Food and Drug Administration (FDA) approved the company’s at-home stool DNA screening test, Cologuard, for the noninvasive detection of colorectal cancers and pre-cancers.[3][4][5]

A 10,000-patient pivotal trial found that the test identified 92 percent of colon cancers and 69 percent of high-risk precancers (high-grade dysplasia) that are most likely to develop into cancer with 87 percent specificity.[6] The results of this study were published in the April 2014 issue of the New England Journal of Medicine.[7]

Stool DNA testing is included in the colorectal cancer screening guidelines of the American Cancer Society.[8]

Exact Sciences is now developing a pipeline of diagnostic tests for the early detection of lung, pancreatic and esophageal cancers.[9]

The company was named to the InBusiness Madison “Best Companies to Work For” list in 2014[10] and received a 2015 American Business Awards Gold Stevie for Company of the Year in the Health Products & Services category.[11]

References

  1. ↑ "MarketWatch citation". MarketWatch. Retrieved 9 September 2015.
  2. ↑ McBride, Ryan (June 18, 2009). "Exact Sciences Moving to Wisconsin". Xconomy. Retrieved 9 September 2015.
  3. ↑ "FDA approves first non-invasive DNA screening test for colorectal cancer". U.S. Food and Drug Administration. FDA. Retrieved 9 September 2015.
  4. ↑ Edney, Anna (August 12, 2014). "Exact Sciences Wins U.S. Approval for Colon Cancer Test". Bloomberg. Retrieved 9 September 2015.
  5. ↑ Schattner, Elaine (March 6, 2015). "For Colon Cancer Screening, Cologuard Test Offers A Solid New Option". Forbes. Retrieved 9 September 2015.
  6. ↑ Jaslow, Ryan (March 19, 2014). "New DNA test may provide non-invasive alternative for colon cancer screening". CBS News. Retrieved 9 September 2015.
  7. ↑ Imperiale, Thomas F.; Ransohoff, David F.; Itzkowitz, Steven H.; Levin, Theodore R.; Lavin, Philip; Lidgard, Graham P.; Ahlquist, David A.; Berger, Barry M. (3 April 2014). "Multitarget Stool DNA Testing for Colorectal-Cancer Screening". New England Journal of Medicine 370 (14): 1287–1297. doi:10.1056/NEJMoa1311194. PMID 24645800. Retrieved 9 September 2015.
  8. ↑ "Colorectal cancer screening tests". American Cancer Society. American Cancer Society. Retrieved 9 September 2015.
  9. ↑ Engel, Jeff (June 30, 2015). "Exact Sciences Outlines Pipeline of Diagnostics for Deadliest Cancers". Xconomy. Retrieved 9 September 2015.
  10. ↑ Vanden Plas, Joe. "Best Companies to Work For: 2014" (December 2014). InBusiness. Retrieved 9 September 2015.
  11. ↑ "2015 Company/ Organization Awards Categories Stevie® Award Winners". The American Business Awards. Retrieved 9 September 2015.
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