Ectodomain

An ectodomain is the domain of a membrane protein that extends into the extracellular space (the space outside a cell). Ectodomains are usually the parts of proteins that initiate contact with surfaces, which leads to signal transduction. In SARS-CoV the ectodomain of the spike protein is responsible for attachment to and entry into cells during infection.[1]

See also

References

  1. ↑ Li, X; Pérez, L; Pan, Z; Fan, H (2007). "The transmembrane domain of TACE regulates protein ectodomain shedding". Cell Research 17 (12): 985–98. doi:10.1038/cr.2007.98. PMID 18040288.


This article is issued from Wikipedia - version of the Thursday, August 27, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.