FAM62A

Extended synaptotagmin-like protein 1
Identifiers
Symbols	ESYT1 ; FAM62A; MBC2
External IDs	MGI: 1344426 HomoloGene: 40794 GeneCards: ESYT1 Gene
Gene ontology Molecular function • protein binding • phospholipid binding • metal ion binding Cellular component • endoplasmic reticulum • plasma membrane • membrane • integral component of endoplasmic reticulum membrane • organelle membrane contact site Biological process • lipid transport Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	23344	23943
Ensembl	ENSG00000139641	ENSMUSG00000025366
UniProt	Q9BSJ8	Q3U7R1
RefSeq (mRNA)	NM_001184796	NM_011843
RefSeq (protein)	NP_001171725	NP_035973
Location (UCSC)	Chr 12: 56.12 – 56.14 Mb	Chr 10: 128.51 – 128.53 Mb
PubMed search

Extended synaptotagmin-1 is a protein in humans that is encoded by the ESYT1 gene.^[1][2][3][4]

References

1. Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Apr 1999). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.
2. Morris NJ, Ross SA, Neveu JM, Lane WS, Lienhard GE (Jul 1999). "Cloning and preliminary characterization of a 121 kDa protein with multiple predicted C2 domains". Biochim Biophys Acta 1431 (2): 525–30. doi:10.1016/S0167-4838(99)00068-0. PMID 10350628.
3. Craxton M (Sep 2007). "Evolutionary genomics of plant genes encoding N-terminal-TM-C2 domain proteins and the similar FAM62 genes and synaptotagmin genes of metazoans". BMC Genomics 8: 259. doi:10.1186/1471-2164-8-259. PMC 1976326. PMID 17672888.
4. "Entrez Gene: FAM62A family with sequence similarity 62 (C2 domain containing), member A".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Bouwmeester T, Bauch A, Ruffner H; et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rush J, Moritz A, Lee KA; et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nat. Biotechnol. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455.