FAM62B

Extended synaptotagmin-like protein 2
PDB rendering based on 2dmg.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 2DMG​, 4NPJ​, 4NPK​, 4P42​
Identifiers
Symbols	ESYT2 ; CHR2SYT; E-Syt2; FAM62B
External IDs	MGI: 1261845 HomoloGene: 32699 GeneCards: ESYT2 Gene
Gene ontology Molecular function • calcium ion binding • protein binding • calcium-dependent phospholipid binding • phosphatidylethanolamine binding • phosphatidylcholine binding • phosphatidylinositol binding • identical protein binding Cellular component • endoplasmic reticulum • integral component of plasma membrane • membrane • intrinsic component of endoplasmic reticulum membrane • extrinsic component of cytoplasmic side of plasma membrane • organelle membrane contact site Biological process • lipid transport • endocytosis Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	57488	52635
Ensembl	ENSG00000117868	ENSMUSG00000021171
UniProt	A0FGR8	Q3TZZ7
RefSeq (mRNA)	NM_020728	NM_028731
RefSeq (protein)	NP_065779	NP_083007
Location (UCSC)	Chr 7: 158.73 – 158.83 Mb	Chr 12: 116.28 – 116.37 Mb
PubMed search

Extended synaptotagmin-2 is a protein that in humans is encoded by the ESYT2 gene.^[1][2]

References

1. Craxton M (Sep 2007). "Evolutionary genomics of plant genes encoding N-terminal-TM-C2 domain proteins and the similar FAM62 genes and synaptotagmin genes of metazoans". BMC Genomics 8: 259. doi:10.1186/1471-2164-8-259. PMC 1976326. PMID 17672888.
2. "Entrez Gene: FAM62B family with sequence similarity 62 (C2 domain containing) member B".

Further reading

• Nakajima D, Okazaki N, Yamakawa H; et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
• Nagase T, Ishikawa K, Kikuno R; et al. (2000). "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 6 (5): 337–45. doi:10.1093/dnares/6.5.337. PMID 10574462.
• Craxton M (2001). "Genomic analysis of synaptotagmin genes.". Genomics 77 (1-2): 43–9. doi:10.1006/geno.2001.6619. PMID 11543631.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Scherer SW, Cheung J, MacDonald JR; et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Beausoleil SA, Jedrychowski M, Schwartz D; et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Foster LJ, Rudich A, Talior I; et al. (2006). "Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC).". J. Proteome Res. 5 (1): 64–75. doi:10.1021/pr0502626. PMID 16396496.