FKBP8

FK506 binding protein 8, 38kDa

PDB rendering based on 2awg.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols FKBP8 ; FKBP38; FKBPr38
External IDs OMIM: 604840 MGI: 1341070 HomoloGene: 7720 GeneCards: FKBP8 Gene
EC number 5.2.1.8
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 23770 14232
Ensembl ENSG00000105701 ENSMUSG00000019428
UniProt Q14318 O35465
RefSeq (mRNA) NM_001308373 NM_001111066
RefSeq (protein) NP_001295302 NP_001104536
Location (UCSC) Chr 19:
18.53 – 18.54 Mb
Chr 8:
70.53 – 70.54 Mb
PubMed search

FK506-binding protein 8 is a protein that in humans is encoded by the FKBP8 gene.[1][2]

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, this encoded protein does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function.[2]

References

  1. Lam E, Martin M, Wiederrecht G (Sep 1995). "Isolation of a cDNA encoding a novel human FK506-binding protein homolog containing leucine zipper and tetratricopeptide repeat motifs". Gene 160 (2): 297–302. doi:10.1016/0378-1119(95)00216-S. PMID 7543869.
  2. 1 2 "Entrez Gene: FKBP8 FK506 binding protein 8, 38kDa".

Further reading

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