FMN reductase (NADH)

FMN reductase (NADH) (EC 1.5.1.42, NADH-FMN reductase) is an enzyme with systematic name FMNH₂:NAD⁺ oxidoreductase.^[1]^[2]^[3]^[4] This enzyme catalyses the following chemical reaction

FMNH₂ + NAD⁺

\rightleftharpoons

FMN + NADH + H⁺

The enzyme often forms a complex with monooxygenases.

References

↑ Duane, W. and Hastings, J.W. (1975). "Flavin mononucleotide reductase of luminous bacteria". Mol. Cell. Biochem. 6: 53–64. doi:10.1007/BF01731866. PMID 47604.
↑ Gerlo, E. and Charlier, J. (1975). "Identification of NADH-specific and NADPH-specific FMN reductases in Beneckea harveyi". Eur. J. Biochem. 57 (2): 461–467. doi:10.1111/j.1432-1033.1975.tb02321.x. PMID 1175652.
↑ Uetz, T., Schneider, R., Snozzi, M. and Egli, T. (1992). "Purification and characterization of a two-component monooxygenase that hydroxylates nitrilotriacetate from "Chelatobacter" strain ATCC 29600". J. Bacteriol. 174 (4): 1179–1188. PMC 206410. PMID 1735711.
↑ Izumoto, Y., Mori, T. and Yamamoto, K. (1994). "Cloning and nucleotide sequence of the gene for NADH:FMN oxidoreductase from Vibrio harveyi". Biochim. Biophys. Acta 1185 (2): 243–246. doi:10.1016/0005-2728(94)90216-x. PMID 8167139.

External links

FMN reductase (NADH) at the US National Library of Medicine Medical Subject Headings (MeSH)

Oxidoreductases: CH-NH (EC 1.5)

1.5.1: NAD or NADP acceptor	Dihydrofolate reductase Saccharopine dehydrogenase Methylenetetrahydrofolate reductase

1.5.3: oxygen acceptor	Dihydrobenzophenanthridine oxidase Sarcosine oxidase Proline oxidase

1.5.5: quinone acceptor	Electron-transferring-flavoprotein dehydrogenase

1.5.99	Sarcosine dehydrogenase Cytokinin dehydrogenase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

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