Grapevine fanleaf virus
| Grapevine fanleaf virus (GFLV) | |
|---|---|
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| Crystal structure of Grapevine Fanleaf Virus capsid. PDB entry 2y26[1] | |
| Virus classification | |
| Group: | Group IV ((+)ssRNA) |
| Order: | Picornavirales |
| Family: | Secoviridae |
| Subfamily: | Comovirinae |
| Genus: | Nepovirus |
| Species: | Grapevine fanleaf virus |
| Synonyms | |
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Grapevine fanleaf virus (GFLV) is a plant pathogenic virus of the family Secoviridae. It infects grapevines, causing chlorosis of the leaves and lowering the fruit quality.[2] Because of its effect on grape yield, GFLV is a pathogen of commercial importance. It is transmitted via a nematode vector, Xiphinema index.[3] This nematode acquires the virus through feeding on roots of an infected plant, and passes it on in the same manner.
The virus has an RNA genome contained on two RNA molecules, each of which is covalently attached to a small protein (the viral genome-linked protein, VPg) at the 5' end.[2] Each RNA encodes a single open reading frame, coding for a polyprotein. The longer polyprotein (the product of RNA1) is cleaved into five functional proteins, including the viral RNA polymerase[4] and the shorter (from RNA2) is cleaved into three proteins. The coat protein derives from RNA2[5] and forms the icosahedral capsid of 60 identical protein subunits.[1]
External links
- ICTVdB—The Universal Virus Database: Grapevine fanleaf virus
- Family Groups—The Baltimore Method
- Taxonomy Browser at PDBe
References
- 1 2 Schellenberger, P.; Sauter, C.; Lorber, B.; Bron, P.; Trapani, S.; Bergdoll, M.; Marmonier, A. L.; Schmitt-Keichinger, C.; Lemaire, O.; Demangeat, G. R.; Ritzenthaler, C. (2011). Nagy, Peter D, ed. "Structural Insights into Viral Determinants of Nematode Mediated Grapevine fanleaf virus Transmission". PLoS Pathogens 7 (5): e1002034. doi:10.1371/journal.ppat.1002034. PMC 3098200. PMID 21625570.
- 1 2 P. Andret-Link et al. Journal of Plant Pathology (2004), 86(3), 183–195
- ↑ Andret-Link, P.; Schmitt-Keichinger, C.; Demangeat, G. R.; Komar, V. R.; Fuchs, M. (2004). "The specific transmission of Grapevine fanleaf virus by its nematode vector Xiphinema index is solely determined by the viral coat protein". Virology 320 (1): 12–22. doi:10.1016/j.virol.2003.11.022. PMID 15003859.
- ↑ Ritzenthaler, C.; Viry, M.; Pinck, M.; Margis, R.; Fuchs, M.; Pinck, L. (1991). "Complete nucleotide sequence and genetic organization of grapevine fanleaf nepovirus RNA1". The Journal of general virology. 72 ( Pt 10) (10): 2357–2365. doi:10.1099/0022-1317-72-10-2357. PMID 1655953.
- ↑ Serghini, M. A.; Fuchs, M.; Pinck, M.; Reinbolt, J.; Walter, B.; Pinck, L. (1990). "RNA2 of grapevine fanleaf virus: Sequence analysis and coat protein cistron location". The Journal of general virology. 71 ( Pt 7) (7): 1433–1441. doi:10.1099/0022-1317-71-7-1433. PMID 2374004.