Farnesylcysteine lyase

Farnesylcysteine lyase (EC 1.8.3.6, FC lyase, FCLY) is an enzyme with systematic name S-(2E,6E)-farnesyl-L-cysteine oxidase.^[1]^[2] This enzyme catalyses the following chemical reaction

S-(2E,6E)-farnesyl-L-cysteine + O₂ + H₂O

\rightleftharpoons

(2E,6E)-farnesal + L-cysteine + H₂O₂

Farnesylcysteine lyase is a flavoprotein (FAD).

References

↑ Huizinga, D.H., Denton, R., Koehler, K.G., Tomasello, A., Wood, L., Sen, S.E. and Crowell, D.N. (2010). "Farnesylcysteine lyase is involved in negative regulation of abscisic acid signaling in Arabidopsis". Mol Plant 3 (1): 143–155. doi:10.1093/mp/ssp091. PMC 2807925. PMID 19969520.
↑ Crowell, D.N., Huizinga, D.H., Deem, A.K., Trobaugh, C., Denton, R. and Sen, S.E. (2007). "Arabidopsis thaliana plants possess a specific farnesylcysteine lyase that is involved in detoxification and recycling of farnesylcysteine". Plant J. 50 (5): 839–847. doi:10.1111/j.1365-313X.2007.03091.x. PMID 17425716.

External links

Farnesylcysteine lyase at the US National Library of Medicine Medical Subject Headings (MeSH)

Oxidoreductases: sulfur oxidoreductases (EC 1.8)

1.8.1: NAD or NADP	Dihydrolipoamide dehydrogenase Glutathione reductase Thioredoxin reductase

1.8.2: cytochrome	Sulfite dehydrogenase Thiosulfate dehydrogenase

1.8.3: oxygen	Sulfite oxidase

1.8.4: disulfide	Glutathione—homocystine transhydrogenase

1.8.5: quinone	Glutathione dehydrogenase (ascorbate)

1.8.98: Other, known	CoB—CoM heterodisulfide reductase

1.8.99: Other	Sulfite reductase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

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