Film coating

A film coating is a thin polymer-based coat applied to a solid dosage form such as a tablet. The thickness of such a coating is usually between 20-100 µm.[1] It is possible to follow the dynamic curing effect on tablet coating structure by using non-destructive analytical methodologies.[2]

Film coating formulations usually contain the following components:

  1. Polymer
  2. Plasticizer
  3. Colourant
  4. Opacifier
  5. Solvent
  6. Vehicle

Functionality wise it is further divided into:

  1. Immediate release coating
  2. Sustained release or modified release coating
  3. Enteric release coating

References

  1. ↑ Felton, Linda A; Porter, Stuart C (2013). "An update on pharmaceutical film coating for drug delivery". Expert Opinion on Drug Delivery 10 (4): 421–35. doi:10.1517/17425247.2013.763792. PMID 23339342.
  2. ↑ Gendre C., Genty M., César da Silva J., Tfayli A., Boiret M., Lecoq O., Baron M., Chaminade P., Péan J-M., Comprehensive study of dynamic curing effect on tablet coating structure, Eur. J. Pharm. Biopharm., 81 (2012), 657-665
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