Finrozole

Finrozole
Names

IUPAC name 4-[(1R,2S)-3-(4-Fluorophenyl)-2-hydroxy-1-(1,2,4-triazol-1-yl)propyl]benzonitrile
Identifiers
CAS Number	160146-17-8
ChEMBL	ChEMBL2218882
Jmol interactive 3D	Image
PubChem	6918277
InChI InChI=1S/C18H15FN4O/c19-16-7-3-13(4-8-16)9-17(24)18(23-12-21-11-22-23)15-5-1-14(10-20)2-6-15/h1-8,11-12,17-18,24H,9H2/t17-,18+/m0/s1 Key: SLJZVZKQYSKYNV-ZWKOTPCHSA-N
SMILES C1=CC(=CC=C1C[C@@H]([C@@H](C2=CC=C(C=C2)C#N)N3C=NC=N3)O)F
Properties
Chemical formula	C₁₈H₁₅FN₄O
Molar mass	322.34 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Finrozole is an aromatase (CYP19A1) inhibitor.^[1]

References

↑ Huuskonen, P; Myllynen, P; Storvik, M; Pasanen, M (2013). "The effects of aflatoxin B1 on transporters and steroid metabolizing enzymes in JEG-3 cells". Toxicology letters 218 (3): 200–6. doi:10.1016/j.toxlet.2013.01.015. PMID 23402939.

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