Flight 1

Flight 1 or Flight 001 may refer to:

• American Airlines Flight 1, a Boeing 707 that crashed after a rudder failure in 1962
  • "Flight 1", an episode of the television show Mad Men, centering in part on the American Airlines crash
• Qantas Flight 1, a flight that overran the runway in Bangkok in 1999
• Northwest Airlines Flight 1, a Lockheed Super Electra that suffered a fire on board and crashed in 1939
• Icelandic Airlines Flight 001, a Douglas DC-8 that crashed in Sri Lanka in 1978
• CSA Flight 001, a flight that crashed in Czechoslovakia in 1976