Nodavirus endopeptidase

Nodavirus endopeptidase
Identifiers
EC number 3.4.23.44
CAS number 852954-38-2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Nodavirus endopeptidase (EC 3.4.23.44, Black Beetle virus endopeptidase, Flock House virus endopeptidase) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Hydrolysis of an asparaginyl bond involved in the maturation of the structural protein of the virus, typically -Asn-Ala- or -Asn-Phe-

The enzyme is coded by several nodaviruses that are insect pathogens.

References

  1. Zlotnick, A., Reddy, V.S., Dasgupta, R., Schneemann, A. (1994). ", Ray,W.J., Jr., Rueckert, R.R. and Johnson, J.E. Capsid assembly in a family of animal viruses primes an autoproteolytic maturation that depends on a single aspartic acid residue". J. Biol. Chem. 269: 13680–13684. PMID 8175803.
  2. Johnson, J.E. and Schneemann, A. (1998). "Nodavirus endopeptidase". In Barrett, A.J., Rawlings, N.D. and Woessner, J.F. Handbook of Proteolytic Enzymes. London: Handbook of Proteolytic Enzymes. pp. 964–967.

External links

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