Fluvalinate

Fluvalinate

Systematic (IUPAC) name
[Cyano-(3-phenoxyphenyl)methyl] 2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	69409-94-5 102851-06-9 (tau-fluvalinate)
ATCvet code	QP53AC10(WHO)
PubChem	CID 50516
ChemSpider	45805
KEGG	C18790
Chemical data
Formula	C26H22ClF3N2O3
Molar mass	502.913 g/mol
SMILES CC(C)C(C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl
InChI InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3 Key:INISTDXBRIBGOC-UHFFFAOYSA-N
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Fluvalinate (trade names include Apistan, Klartan, Minadox) is a synthetic pyrethroid commonly used to control varroa mites in honey bee colonies.

Fluvalinate is a stable, non-volatile, fat-soluble compound. Fluvalinate effectiveness was demonstrated in France and Israel. Although the compound may be found in drones, a study has found honey samples virtually absent of fluvalinate, on account of its affinity to beeswax.^[1]

Tau-fluvalinate (τ-fluvalinate) is the trivial name for (2R)-fluvalinate. The C atom in the valinate structure is in D-configuration, while the second chiral atom is a mixture of both R and S.

See also

• EPA: Tau-fluvalinate; Reregistration Eligibility Decision for Low Risk Pesticide; Notice of Availability
• Tau-fluvalinate in the Pesticide Properties DataBase (PPDB)
• Fluvalinate in the Pesticide Properties DataBase (PPDB)

References

1. A Review of Treatment Options for Control of Varroa Mite in New Zealand http://www.biosecurity.govt.nz/pests-diseases/animals/varroa/paper/varroa-treatment-options.htm#4 MAF Biosecurity New Zealand